Kinetics of antibody response in unprimed recipients after transfer of immune lymphocytes.

L. Varesio, S. Landolfo, G. Cavallo

Research output: Contribution to journalArticle

Abstract

Spleen cells from mice immunized with SRBC were transferred, at various times after immunization, to non-irradiated and lethally irradiated syngeneic recipients. The PFC kinetics and anti-SRBC antibody titres were followed in various groups of mice. Similar results were obtained both in non-irradiated and lethally irradiated recipients, showing that after the transfer: a) PFC proliferation was blocked, b) PFC blocking was unrelated to their maturation stage, c) resting PFC were still able to synthesize antibodies, d) blocking activity was radio-resistant.

Original languageEnglish
Pages (from-to)264-269
Number of pages6
JournalFolia Biologica
Volume24
Issue number4
Publication statusPublished - 1978

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Agricultural and Biological Sciences (miscellaneous)

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