SYNDROME DE KLINEFELTER (DYSGENESIE GONADIQUE AVEC CARYOTYPE 47,XXY) ET EPILEPSIE: 5 OBSERVATIONS

Translated title of the contribution: Klinefelter syndrome and epilepsy: 5 Cases

P. Genton, M. T. Medina, J. Roger, M. Murcia de Medina, M. G. Mattei, R. Guerrini

Research output: Contribution to journalArticlepeer-review

Abstract

The Klinefelter syndrome (KS) is characterized by a 47, XXY karyotype resulting in primary hypogonadism associated with mental retardation in 15 to 20% of cases. While abnormal EEGs were found in a large subset of patients, only 7 cases of KS associated with epilepsy have been reported; the prevalence of epilepsy in KS patients is thought to be around 17%. Among 143 consecutive KS patients diagnosed at a mean age of 23 years, we found 7 cases with epilepsy (4,9%), among which 5 were followed at our center. The epilepsy was classified as situation-related seizures (n = 1), generalized idiopathic (n = 2) and partial cryptogenic (n = 2). The additional X chromosome may be implied in the occurrence of epilepsy.

Translated title of the contributionKlinefelter syndrome and epilepsy: 5 Cases
Original languageFrench
Pages (from-to)69-70
Number of pages2
JournalBollettino - Lega Italiana contro l'Epilessia
Issue number79-80
Publication statusPublished - 1992

ASJC Scopus subject areas

  • Clinical Neurology

Fingerprint Dive into the research topics of 'Klinefelter syndrome and epilepsy: 5 Cases'. Together they form a unique fingerprint.

Cite this