Klotho in acute kidney injury: Biomarker, therapy, or a bit of both

Sistiana Aiello, Marina Noris

Research output: Contribution to journalArticle

Abstract

Acute kidney injury (AKI) diagnosis is based on an increase in serum creatinine or a decrease in urine output. To be effective, treatment of AKI should be started very early after the insult and well before the rise of serum creatinine. Thus, sensitive biologic markers of renal tubular injury in AKI are strongly needed. Hu et al. suggest that Klotho could be a novel biomarker and therapeutic target of ischemia-induced AKI.

Original languageEnglish
Pages (from-to)1208-1210
Number of pages3
JournalKidney International
Volume78
Issue number12
DOIs
Publication statusPublished - Dec 2010

ASJC Scopus subject areas

  • Nephrology

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