Koebner's phenomenon in vitiligo: European position paper

Nanja van Geel, Reinhart Speeckaert, Alain Taieb, Mauro Picardo, Markus Böhm, David J. Gawkrodger, Karin Schallreuter, Dorothy C. Bennett, Wietze van der Veen, Maxine Whitton, Silvia Moretti, Wiete Westerhof, Khaled Ezzedine, Yvon Gauthier

Research output: Contribution to journalArticlepeer-review


Koebner's phenomenon (KP) has been observed in a number of skin diseases, including vitiligo. Its clinical significance in vitiligo with respect to disease activity and course is still debatable, while its relevance for surgical techniques has been demonstrated in some reports. We present a literature review on the currently known facts about KP in vitiligo, including details of clinical, experimental, and histopathological changes. The consensus view is that there are still no methods to define and assess KP in vitiligo. A new classification is proposed to allow an evaluation of KP in daily practice or in experimental studies. However, many unanswered questions still remain after redefining KP in patients with vitiligo. Active research focusing on KP in vitiligo may not only provide unexpected clues in the pathogenesis of vitiligo but also help to tailor novel therapies against this chronic and often psychologically devastating skin disease.

Original languageEnglish
Pages (from-to)564-573
Number of pages10
JournalPigment Cell and Melanoma Research
Issue number3
Publication statusPublished - Jun 2011


  • Isomorphic response
  • Koebner's phenomenon
  • Melanocytorrhagy
  • Pathogenesis
  • Review
  • Trauma
  • Vitiligo

ASJC Scopus subject areas

  • Dermatology
  • Oncology
  • Biochemistry, Genetics and Molecular Biology(all)


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