KPC-Like Carbapenemase-Producing Enterobacteriaceae Colonizing Patients in Europe and Israel

A. Baraniak; R. Izdebski; J. Fiett; M. Herda; L. P G Derde; M. J M Bonten; A. Adler; Y. Carmeli; H. Goossens; W. Hryniewicz; C. Brun-Buisson; Marek Gniadkowski; MOSAR WP2, WP3, and WP5 Study Groups; Angelo Rossini; Antonino Salvia

doi:10.1128/AAC.02756-15

KPC-Like Carbapenemase-Producing Enterobacteriaceae Colonizing Patients in Europe and Israel

A. Baraniak, R. Izdebski, J. Fiett, M. Herda, L. P G Derde, M. J M Bonten, A. Adler, Y. Carmeli, H. Goossens, W. Hryniewicz, C. Brun-Buisson, Marek Gniadkowski, MOSAR WP2, WP3, and WP5 Study Groups, Angelo Rossini, Antonino Salvia

Fondazione Santa Lucia

Research output: Contribution to journal › Article › peer-review

Abstract

In a 2008-2011 survey, 17,945 patients in 18 hospital units in Europe and Israel were screened for carriage of Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae, resulting in identification of 124 positive patients. The isolates were dominated by Klebsiella pneumoniae sequence type 258 (ST258) KPC-2 and ST512 KPC-3, mainly from Greece and Italy, respectively, whereas Israeli isolates were of diverse species, clones, and KPC variants. Various blaKPC platforms were observed, among which IncFIIK-FIBK plasmids with blaKPC-2/-3 genes in the Tn4401a transposon prevailed.

Original language	English
Pages (from-to)	1912-7
Number of pages	6
Journal	Antimicrobial Agents and Chemotherapy
Volume	60
Issue number	3
DOIs	https://doi.org/10.1128/AAC.02756-15
Publication status	Published - 2016

Keywords

Anti-Bacterial Agents
Bacterial Proteins
Carbapenems
Citrobacter freundii
DNA Transposable Elements
Enterobacteriaceae Infections
Escherichia coli
Europe
Humans
Israel
Klebsiella pneumoniae
Plasmids
beta-Lactamases
Journal Article
Research Support, Non-U.S. Gov't

Access to Document

10.1128/AAC.02756-15

Cite this

Baraniak, A., Izdebski, R., Fiett, J., Herda, M., Derde, L. P. G., Bonten, M. J. M., Adler, A., Carmeli, Y., Goossens, H., Hryniewicz, W., Brun-Buisson, C., Gniadkowski, M., MOSAR WP2, WP3, and WP5 Study Groups, Rossini, A., & Salvia, A. (2016). KPC-Like Carbapenemase-Producing Enterobacteriaceae Colonizing Patients in Europe and Israel. Antimicrobial Agents and Chemotherapy, 60(3), 1912-7. https://doi.org/10.1128/AAC.02756-15

Baraniak, A, Izdebski, R, Fiett, J, Herda, M, Derde, LPG, Bonten, MJM, Adler, A, Carmeli, Y, Goossens, H, Hryniewicz, W, Brun-Buisson, C, Gniadkowski, M, MOSAR WP2, WP3, and WP5 Study Groups, Rossini, A & Salvia, A 2016, 'KPC-Like Carbapenemase-Producing Enterobacteriaceae Colonizing Patients in Europe and Israel', Antimicrobial Agents and Chemotherapy, vol. 60, no. 3, pp. 1912-7. https://doi.org/10.1128/AAC.02756-15

@article{f9bf028734944aa197648912ba640180,

title = "KPC-Like Carbapenemase-Producing Enterobacteriaceae Colonizing Patients in Europe and Israel",

abstract = "In a 2008-2011 survey, 17,945 patients in 18 hospital units in Europe and Israel were screened for carriage of Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae, resulting in identification of 124 positive patients. The isolates were dominated by Klebsiella pneumoniae sequence type 258 (ST258) KPC-2 and ST512 KPC-3, mainly from Greece and Italy, respectively, whereas Israeli isolates were of diverse species, clones, and KPC variants. Various blaKPC platforms were observed, among which IncFIIK-FIBK plasmids with blaKPC-2/-3 genes in the Tn4401a transposon prevailed.",

keywords = "Anti-Bacterial Agents, Bacterial Proteins, Carbapenems, Citrobacter freundii, DNA Transposable Elements, Enterobacteriaceae Infections, Escherichia coli, Europe, Humans, Israel, Klebsiella pneumoniae, Plasmids, beta-Lactamases, Journal Article, Research Support, Non-U.S. Gov't",

author = "A. Baraniak and R. Izdebski and J. Fiett and M. Herda and Derde, {L. P G} and Bonten, {M. J M} and A. Adler and Y. Carmeli and H. Goossens and W. Hryniewicz and C. Brun-Buisson and Marek Gniadkowski and {MOSAR WP2, WP3, and WP5 Study Groups} and Angelo Rossini and Antonino Salvia",

year = "2016",

doi = "10.1128/AAC.02756-15",

language = "English",

volume = "60",

pages = "1912--7",

journal = "Antimicrobial Agents and Chemotherapy",

issn = "0066-4804",

publisher = "American Society for Microbiology",

number = "3",

}

TY - JOUR

T1 - KPC-Like Carbapenemase-Producing Enterobacteriaceae Colonizing Patients in Europe and Israel

AU - Baraniak, A.

AU - Izdebski, R.

AU - Fiett, J.

AU - Herda, M.

AU - Derde, L. P G

AU - Bonten, M. J M

AU - Adler, A.

AU - Carmeli, Y.

AU - Goossens, H.

AU - Hryniewicz, W.

AU - Brun-Buisson, C.

AU - Gniadkowski, Marek

AU - MOSAR WP2, WP3, and WP5 Study Groups

AU - Rossini, Angelo

AU - Salvia, Antonino

PY - 2016

Y1 - 2016

N2 - In a 2008-2011 survey, 17,945 patients in 18 hospital units in Europe and Israel were screened for carriage of Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae, resulting in identification of 124 positive patients. The isolates were dominated by Klebsiella pneumoniae sequence type 258 (ST258) KPC-2 and ST512 KPC-3, mainly from Greece and Italy, respectively, whereas Israeli isolates were of diverse species, clones, and KPC variants. Various blaKPC platforms were observed, among which IncFIIK-FIBK plasmids with blaKPC-2/-3 genes in the Tn4401a transposon prevailed.

AB - In a 2008-2011 survey, 17,945 patients in 18 hospital units in Europe and Israel were screened for carriage of Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae, resulting in identification of 124 positive patients. The isolates were dominated by Klebsiella pneumoniae sequence type 258 (ST258) KPC-2 and ST512 KPC-3, mainly from Greece and Italy, respectively, whereas Israeli isolates were of diverse species, clones, and KPC variants. Various blaKPC platforms were observed, among which IncFIIK-FIBK plasmids with blaKPC-2/-3 genes in the Tn4401a transposon prevailed.

KW - Anti-Bacterial Agents

KW - Bacterial Proteins

KW - Carbapenems

KW - Citrobacter freundii

KW - DNA Transposable Elements

KW - Enterobacteriaceae Infections

KW - Escherichia coli

KW - Europe

KW - Humans

KW - Israel

KW - Klebsiella pneumoniae

KW - Plasmids

KW - beta-Lactamases

KW - Journal Article

KW - Research Support, Non-U.S. Gov't

U2 - 10.1128/AAC.02756-15

DO - 10.1128/AAC.02756-15

M3 - Article

C2 - 26711772

VL - 60

SP - 1912

EP - 1917

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

SN - 0066-4804

IS - 3

ER -

KPC-Like Carbapenemase-Producing Enterobacteriaceae Colonizing Patients in Europe and Israel

Abstract

Keywords

Access to Document

Fingerprint

Cite this