Abstract
In a 2008-2011 survey, 17,945 patients in 18 hospital units in Europe and Israel were screened for carriage of Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae, resulting in identification of 124 positive patients. The isolates were dominated by Klebsiella pneumoniae sequence type 258 (ST258) KPC-2 and ST512 KPC-3, mainly from Greece and Italy, respectively, whereas Israeli isolates were of diverse species, clones, and KPC variants. Various blaKPC platforms were observed, among which IncFIIK-FIBK plasmids with blaKPC-2/-3 genes in the Tn4401a transposon prevailed.
Original language | English |
---|---|
Pages (from-to) | 1912-7 |
Number of pages | 6 |
Journal | Antimicrobial Agents and Chemotherapy |
Volume | 60 |
Issue number | 3 |
DOIs | |
Publication status | Published - 2016 |
Keywords
- Anti-Bacterial Agents
- Bacterial Proteins
- Carbapenems
- Citrobacter freundii
- DNA Transposable Elements
- Enterobacteriaceae Infections
- Escherichia coli
- Europe
- Humans
- Israel
- Klebsiella pneumoniae
- Plasmids
- beta-Lactamases
- Journal Article
- Research Support, Non-U.S. Gov't