Abstract
In this study, an investigation into the mode of action of L-acetylcarnitine (L-Ac), a naturally occurring substance with properties capable of improving some neuropsychological functions, is described. Seventeen patients with clinical signs and symptoms of cerebrovascular damage giving rise to neurovascular deficits were studied, using a comprehensive series of neuropsychological and clinical tests. Nine of the 17 were given L-Ac orally, 500 mg b.d. for 2-3 months. They were all receiving other drug therapy as necessary and undergoing neurological rehabilitation and antiparalysis therapy. The findings showed an improved performance in attention tests in the nine patients treated with L-Ac as compared to the controls. This is considered possibly due to an overall activation of cognitive functions.
| Original language | English |
|---|---|
| Pages (from-to) | 77-82 |
| Number of pages | 6 |
| Journal | Clinical Trials Journal |
| Volume | 25 |
| Issue number | SUPPL. 1 |
| Publication status | Published - 1988 |
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ASJC Scopus subject areas
- Pharmacology (medical)
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L-acetylcarnitine in stabilized cerebrovascular lesions. A neuropsychological study : preliminary data. / Crisci, C.; Trojano, L.; Lanzillo, B.; Massini, R.; Pappone, N.
In: Clinical Trials Journal, Vol. 25, No. SUPPL. 1, 1988, p. 77-82.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - L-acetylcarnitine in stabilized cerebrovascular lesions. A neuropsychological study
T2 - preliminary data
AU - Crisci, C.
AU - Trojano, L.
AU - Lanzillo, B.
AU - Massini, R.
AU - Pappone, N.
PY - 1988
Y1 - 1988
N2 - In this study, an investigation into the mode of action of L-acetylcarnitine (L-Ac), a naturally occurring substance with properties capable of improving some neuropsychological functions, is described. Seventeen patients with clinical signs and symptoms of cerebrovascular damage giving rise to neurovascular deficits were studied, using a comprehensive series of neuropsychological and clinical tests. Nine of the 17 were given L-Ac orally, 500 mg b.d. for 2-3 months. They were all receiving other drug therapy as necessary and undergoing neurological rehabilitation and antiparalysis therapy. The findings showed an improved performance in attention tests in the nine patients treated with L-Ac as compared to the controls. This is considered possibly due to an overall activation of cognitive functions.
AB - In this study, an investigation into the mode of action of L-acetylcarnitine (L-Ac), a naturally occurring substance with properties capable of improving some neuropsychological functions, is described. Seventeen patients with clinical signs and symptoms of cerebrovascular damage giving rise to neurovascular deficits were studied, using a comprehensive series of neuropsychological and clinical tests. Nine of the 17 were given L-Ac orally, 500 mg b.d. for 2-3 months. They were all receiving other drug therapy as necessary and undergoing neurological rehabilitation and antiparalysis therapy. The findings showed an improved performance in attention tests in the nine patients treated with L-Ac as compared to the controls. This is considered possibly due to an overall activation of cognitive functions.
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UR - http://www.scopus.com/inward/citedby.url?scp=0024234679&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:0024234679
VL - 25
SP - 77
EP - 82
JO - Clinical Trials Journal
JF - Clinical Trials Journal
SN - 0009-9325
IS - SUPPL. 1
ER -