Abstract
This retrospective study was conducted to analyze clinical and laboratoristic parameters to individuate specific differences and facilitate differential diagnosis between Measles and Kawasaki Disease (KD) at first evaluation in an emergency room. We found similar clinical features as duration of fever and number of KD criteria (p > 0.5) but significant differences in white blood cell count, neutrophils, CRP and LDH levels (p < 0.001). LDH value ≥ 800 mg/dl had sensibility of 89% and specificity of 90% for Measles while CRP ≥ 3 mg/dl had sensibility 89% and specificity of 85% for KD. The combined use of CRP, LDH and AST showed accuracy of 86.67%.
| Original language | English |
|---|---|
| Article number | e2018033 |
| Journal | Mediterranean Journal of Hematology and Infectious Diseases |
| Volume | 10 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Jan 1 2018 |
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Keywords
- Kawasaki disease
- Measles
ASJC Scopus subject areas
- Hematology
- Infectious Diseases
Cite this
Laboratory biomarkers to facilitate differential diagnosis between measles and kawasaki disease in a pediatric emergency room : A retrospective study. / Buonsenso, Danilo; Macchiarulo, Giulia; Supino, Maria Chiara; Penna, Francesco La; Scateni, Simona; Marchesi, Alessandra; Reale, Antonino; Boccuzzi, Elena.
In: Mediterranean Journal of Hematology and Infectious Diseases, Vol. 10, No. 1, e2018033, 01.01.2018.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Laboratory biomarkers to facilitate differential diagnosis between measles and kawasaki disease in a pediatric emergency room
T2 - A retrospective study
AU - Buonsenso, Danilo
AU - Macchiarulo, Giulia
AU - Supino, Maria Chiara
AU - Penna, Francesco La
AU - Scateni, Simona
AU - Marchesi, Alessandra
AU - Reale, Antonino
AU - Boccuzzi, Elena
PY - 2018/1/1
Y1 - 2018/1/1
N2 - This retrospective study was conducted to analyze clinical and laboratoristic parameters to individuate specific differences and facilitate differential diagnosis between Measles and Kawasaki Disease (KD) at first evaluation in an emergency room. We found similar clinical features as duration of fever and number of KD criteria (p > 0.5) but significant differences in white blood cell count, neutrophils, CRP and LDH levels (p < 0.001). LDH value ≥ 800 mg/dl had sensibility of 89% and specificity of 90% for Measles while CRP ≥ 3 mg/dl had sensibility 89% and specificity of 85% for KD. The combined use of CRP, LDH and AST showed accuracy of 86.67%.
AB - This retrospective study was conducted to analyze clinical and laboratoristic parameters to individuate specific differences and facilitate differential diagnosis between Measles and Kawasaki Disease (KD) at first evaluation in an emergency room. We found similar clinical features as duration of fever and number of KD criteria (p > 0.5) but significant differences in white blood cell count, neutrophils, CRP and LDH levels (p < 0.001). LDH value ≥ 800 mg/dl had sensibility of 89% and specificity of 90% for Measles while CRP ≥ 3 mg/dl had sensibility 89% and specificity of 85% for KD. The combined use of CRP, LDH and AST showed accuracy of 86.67%.
KW - Kawasaki disease
KW - Measles
UR - http://www.scopus.com/inward/record.url?scp=85049241637&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85049241637&partnerID=8YFLogxK
U2 - 10.4084/MJHID.2018.033
DO - 10.4084/MJHID.2018.033
M3 - Article
AN - SCOPUS:85049241637
VL - 10
JO - Mediterranean Journal of Hematology and Infectious Diseases
JF - Mediterranean Journal of Hematology and Infectious Diseases
SN - 2035-3006
IS - 1
M1 - e2018033
ER -