Objective: We evaluated the possibility that clomiphene citrate resistance in women with polycystic ovary syndrome might be related to altered glucose metabolism. Methods: Ten women showing constant resistance (no ovulation) to 1250 mg of clomiphene citrate, repeated at least three times in a 1-year period, underwent an insulin and glucose metabolism study by oral glucose tolerance test. Results: No association was found between resistance to clomiphene citrate and altered glucose metabolism whereas the latter was related to body weight. Conclusion: Resistance to clomiphene citrate is not associated with the presence of altered glucose metabolism.
|Number of pages||4|
|Journal||Italian Journal of Gynaecology and Obstetrics|
|Publication status||Published - 1993|
ASJC Scopus subject areas
- Obstetrics and Gynaecology