Lack of association between genetic variants in the mannose-binding lectin 2 (MBL2) gene and HPV infection

Paola Parrella, Davide Seripa, Maria G. Matera, Monica Rinaldi, Emanuela Signori, Carolina Gravina, Antonietta P. Gallo, Maria Prencipe, Elvira Grandone, Luciano Mariani, Paola Cordiali, Aldo Di Carlo, Patrizia Stentella, Antonio Pachì, Vito M. Fazio

Research output: Contribution to journalArticlepeer-review

Abstract

Genetic variants in the immunomodulatory gene mannose-binding lectin 2 (MBL2), were associated with risk, severity, and frequency of viral infections. In a case-control setting, we investigated the association of MBL2 functional polymorphisms with Human Papillomas Virus (HPV) infection. No differences between cases (HPV+) and controls (HPV-) were found in the distribution of each single genotypes or allele. Haplotype analysis did not show any difference between HPV+ and HPV- groups.

Original languageEnglish
Pages (from-to)159-162
Number of pages4
JournalEuropean Journal of Epidemiology
Volume22
Issue number3
DOIs
Publication statusPublished - Mar 2007

Keywords

  • Genetic variants
  • Gynecological cancer/cervical
  • Host-virus interaction
  • HPV
  • MBL2

ASJC Scopus subject areas

  • Epidemiology

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