Lack of association between genetic variants in the mannose-binding lectin 2 (MBL2) gene and HPV infection

Paola Parrella; Davide Seripa; Maria G. Matera; Monica Rinaldi; Emanuela Signori; Carolina Gravina; Antonietta P. Gallo; Maria Prencipe; Elvira Grandone; Luciano Mariani; Paola Cordiali; Aldo Di Carlo; Patrizia Stentella; Antonio Pachì; Vito M. Fazio

doi:10.1007/s10654-007-9111-8

Lack of association between genetic variants in the mannose-binding lectin 2 (MBL2) gene and HPV infection

Paola Parrella, Davide Seripa, Maria G. Matera, Monica Rinaldi, Emanuela Signori, Carolina Gravina, Antonietta P. Gallo, Maria Prencipe, Elvira Grandone, Luciano Mariani, Paola Cordiali, Aldo Di Carlo, Patrizia Stentella, Antonio Pachì, Vito M. Fazio

Research output: Contribution to journal › Article › peer-review

Abstract

Genetic variants in the immunomodulatory gene mannose-binding lectin 2 (MBL2), were associated with risk, severity, and frequency of viral infections. In a case-control setting, we investigated the association of MBL2 functional polymorphisms with Human Papillomas Virus (HPV) infection. No differences between cases (HPV⁺) and controls (HPV^-) were found in the distribution of each single genotypes or allele. Haplotype analysis did not show any difference between HPV+ and HPV^- groups.

Original language	English
Pages (from-to)	159-162
Number of pages	4
Journal	European Journal of Epidemiology
Volume	22
Issue number	3
DOIs	https://doi.org/10.1007/s10654-007-9111-8
Publication status	Published - Mar 2007

Keywords

Genetic variants
Gynecological cancer/cervical
Host-virus interaction
HPV
MBL2

ASJC Scopus subject areas

Epidemiology

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Parrella, P., Seripa, D., Matera, M. G., Rinaldi, M., Signori, E., Gravina, C., Gallo, A. P., Prencipe, M., Grandone, E., Mariani, L., Cordiali, P., Di Carlo, A., Stentella, P., Pachì, A., & Fazio, V. M. (2007). Lack of association between genetic variants in the mannose-binding lectin 2 (MBL2) gene and HPV infection. European Journal of Epidemiology, 22(3), 159-162. https://doi.org/10.1007/s10654-007-9111-8

Parrella, P, Seripa, D, Matera, MG, Rinaldi, M, Signori, E, Gravina, C, Gallo, AP, Prencipe, M, Grandone, E, Mariani, L, Cordiali, P, Di Carlo, A, Stentella, P, Pachì, A & Fazio, VM 2007, 'Lack of association between genetic variants in the mannose-binding lectin 2 (MBL2) gene and HPV infection', European Journal of Epidemiology, vol. 22, no. 3, pp. 159-162. https://doi.org/10.1007/s10654-007-9111-8

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abstract = "Genetic variants in the immunomodulatory gene mannose-binding lectin 2 (MBL2), were associated with risk, severity, and frequency of viral infections. In a case-control setting, we investigated the association of MBL2 functional polymorphisms with Human Papillomas Virus (HPV) infection. No differences between cases (HPV+) and controls (HPV-) were found in the distribution of each single genotypes or allele. Haplotype analysis did not show any difference between HPV+ and HPV- groups.",

keywords = "Genetic variants, Gynecological cancer/cervical, Host-virus interaction, HPV, MBL2",

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AU - Parrella, Paola

AU - Seripa, Davide

AU - Matera, Maria G.

AU - Rinaldi, Monica

AU - Signori, Emanuela

AU - Gravina, Carolina

AU - Gallo, Antonietta P.

AU - Prencipe, Maria

AU - Grandone, Elvira

AU - Mariani, Luciano

AU - Cordiali, Paola

AU - Di Carlo, Aldo

AU - Stentella, Patrizia

AU - Pachì, Antonio

AU - Fazio, Vito M.

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AB - Genetic variants in the immunomodulatory gene mannose-binding lectin 2 (MBL2), were associated with risk, severity, and frequency of viral infections. In a case-control setting, we investigated the association of MBL2 functional polymorphisms with Human Papillomas Virus (HPV) infection. No differences between cases (HPV+) and controls (HPV-) were found in the distribution of each single genotypes or allele. Haplotype analysis did not show any difference between HPV+ and HPV- groups.

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KW - Gynecological cancer/cervical

KW - Host-virus interaction

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Lack of association between genetic variants in the mannose-binding lectin 2 (MBL2) gene and HPV infection

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Keywords

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