In our case-control study we analyzed two functional IL18 gene promoter polymorphisms (-137 G/C and -607 C/A) and an additional polymorphism at position -656 (G/T) in Alzheimer patients and healthy controls in order to verify the involvement of these genetic variations in the onset of Alzheimer disease. No significant differences were detected for the three IL18 SNPs between AD patients and controls. The haplotypes distribution also did not show any difference within AD subjects and controls.
|Number of pages||3|
|Journal||Neurobiology of Aging|
|Publication status||Published - Jan 2010|
ASJC Scopus subject areas
- Clinical Neurology
- Developmental Biology
- Geriatrics and Gerontology