Lack of effect of short-term lisinopril administration on left ventricular filling dynamics in hypertensive patients with diastolic dysfunction

C. Cuspidi, L. Lonati, L. Sampieri, G. Leonetti, M. L. Muiesan, E. Agabiti-Rosei, A. Zanchetti

Research output: Contribution to journalArticlepeer-review

Abstract

Arterial hypertension may be associated with altered left ventricular filling dynamics. The specific goal of this study was to evaluate whether short-term administration of the ACE inhibitor lisinopril in hypertensive patients with an altered diastolic pattern induced an improvement of left ventricular dynamics, assessed by the echocardio-Doppler technique, independently of effects on left ventricular mass. In a double-blind cross- over study 39 essential hypertensive patients with a ratio of peak early to peak atrial velocity (E/A)

Original languageEnglish
Pages (from-to)307-312
Number of pages6
JournalBlood Pressure
Volume6
Issue number5
Publication statusPublished - Sep 1997

Keywords

  • Diastolic dysfunction
  • Echo-Doppler
  • Hypertension
  • Lisinopril

ASJC Scopus subject areas

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine

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