Lack of effect of simultaneous growth hormone-releasing hormone and naloxone infusions on growth hormone (GH) secretion in normal men

F. Barbetti, M. Cappa, P. Del Balzo, A. Grossi, R. Salvatori, G. Tamburrano

Research output: Contribution to journalArticle

Abstract

Recent studies (in vitro) have demonstrated that stimulatory effect of GH-RH on somatostatin release from hypothalamic cells in culture is probably mediated by beta-endorphin. Conflicting results are reported on the influence of Naloxone on GH secretion in humans. Our data seems to support the view that opioid receptor blockade is not able to modify GH secretion during GH-RH infusion in normal males.

Original languageEnglish
Pages (from-to)97-100
Number of pages4
JournalNeuroendocrinology Letters
Volume10
Issue number2
Publication statusPublished - 1988

ASJC Scopus subject areas

  • Endocrinology
  • Neuroscience(all)

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