Lack of effects of recombinant human growth hormone in a child with a complex cardiovascular malformation and dilated cardiomyopathy

Luca Rosti, E. Cerini, P. Festa, A. Miola, V. Brunelli, A. Frigiola

Research output: Contribution to journalArticlepeer-review

Abstract

Recent studies have suggested the beneficial effects of GH treatment in patients with dilated cardiomyopathy. We have treated with recombinant human growth hormone (rhGH) a 6-year-old female with a complex congenital heart defect (severe tricuspid hypoplasia and malposition of the great arteries), who developed a progressive dilated cardiomyopathy of unknown etiology. rhGH treatment (0,1 U/kg/day, for 3 months) did not improve cardiac function, nor clinical symptoms, although we have no clear explanations for this. However, a trial with rhGH may be offered to children with dilated cardiomyopathy and waiting for heart transplantation. (C)2000, Editrice Kurtis.

Original languageEnglish
Pages (from-to)28-30
Number of pages3
JournalJournal of Endocrinological Investigation
Volume23
Issue number1
Publication statusPublished - 2000

Keywords

  • Congenital heart disease
  • Dilated cardiomyopathy
  • Growth hormone
  • Heart failure

ASJC Scopus subject areas

  • Endocrinology

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