Lack of electrocardiographic changes in women with polycystic ovary syndrome

Francesco Orio, Stefano Palomba, Teresa Cascella, Francesco Manguso, Laura Vuolo, Domenico Tafuri, Carlo Vigorito, Gaetano Lombardi, Vincenzo Liguori, Annamaria Colao, Francesco Giallauria

Research output: Contribution to journalArticlepeer-review


Objective: The aim of the present study was to investigate the potential alterations in electrocardiographic (ECG) pattern in patients with polycystic ovary syndrome (PCOS). Patients: Fifty PCOS patients and 50 age- and body mass index-matched healthy women were studied. Methods: We assessed hormonal and metabolic pattern, and performed ECG analysis for evaluating PQ interval, QRS duration, minimum and maximum QT interval corrected for heart rate (QT cmin and QTcmax, respectively), corrected QT dispersion (QTcd), corrected J point/T-wave interval (JTendc), corrected JTmax interval (JTmaxc), and corrected Tmax-end interval (Tmax-endc). Results: QTcmin (399 ± 21 vs. 396 ± 25 ms, P = 0.51); QTc max (445 ± 25 vs. 443 ± 27 ms, P = 0.70); and QTcd (46 ± 13 vs. 47 ± 15 ms, P = 0.72); JTendc (337 ± 14 vs. 336 ± 16 ms1/2, P = 0.74); and JTmaxc (256 ± 22 vs. 258 ± 21 ms 1/2, P = 0.64); Tmax-endc (81 ± 18 vs. 78 ± 19 ms1/2, P = 0.42) were not significantly different between PCOS and healthy women. Conclusion: Despite profound differences in hormonal and metabolic pattern, our data demonstrate no significant difference in ECG pattern in PCOS compared to healthy controls.

Original languageEnglish
Pages (from-to)46-50
Number of pages5
JournalClinical Endocrinology
Issue number1
Publication statusPublished - Jul 2007

ASJC Scopus subject areas

  • Endocrinology


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