Lack of electrocardiographic changes in women with polycystic ovary syndrome

Objective: The aim of the present study was to investigate the potential alterations in electrocardiographic (ECG) pattern in patients with polycystic ovary syndrome (PCOS). Patients: Fifty PCOS patients and 50 age- and body mass index-matched healthy women were studied. Methods: We assessed hormonal and metabolic pattern, and performed ECG analysis for evaluating PQ interval, QRS duration, minimum and maximum QT interval corrected for heart rate (QT _cmin and QT_cmax, respectively), corrected QT dispersion (QT_cd), corrected J point/T-wave interval (JTend_c), corrected JTmax interval (JTmax_c), and corrected Tmax-end interval (Tmax-end_c). Results: QT_cmin (399 ± 21 vs. 396 ± 25 ms, P = 0.51); QT_c max (445 ± 25 vs. 443 ± 27 ms, P = 0.70); and QT_cd (46 ± 13 vs. 47 ± 15 ms, P = 0.72); JTend_c (337 ± 14 vs. 336 ± 16 ms^1/2, P = 0.74); and JTmax_c (256 ± 22 vs. 258 ± 21 ms ^1/2, P = 0.64); Tmax-end_c (81 ± 18 vs. 78 ± 19 ms^1/2, P = 0.42) were not significantly different between PCOS and healthy women. Conclusion: Despite profound differences in hormonal and metabolic pattern, our data demonstrate no significant difference in ECG pattern in PCOS compared to healthy controls.