Lack of evidence for an impairment of tuberoinfundibolar dopaminergic neurons in aged male rats of the sprague-dawley strain

S. Amoroso, G. F. Di Renzo, F. Maurano, P. Maida, M. Tagliatatela, L. Annunziato

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Circulating prolactin (PRL) levels, dopamine (DA) content, in vitro basal and stimulus-evoked endogenous DA release from arcuate-periventricular nuclei median-eminence fragments were studied in young (4 months) and old (24-25 months) male rats of Sprague-Dawley strain. Serum PRL levels did not differ in young and aged animals. In addition DA tissue content, basal and K+- or d-amphetamine evoked endogenous DA release did not show age-related differences. These results suggest that in male rats of the Sprague-Dawley strain the activity of tuberoinfundibular dopaminergic (TIDA) neurons does not change during senescence, unlike what happens in other strains of rats.

Original languageEnglish
Pages (from-to)85-87
Number of pages3
JournalExperimental Aging Research
Volume13
Issue number2
DOIs
Publication statusPublished - 1987

Fingerprint

Dopaminergic Neurons
Sprague Dawley Rats
Dopamine
Prolactin
Dextroamphetamine
Median Eminence
Arcuate Nucleus of Hypothalamus
Neuron
Impairment
Rat
Serum

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Arts and Humanities (miscellaneous)
  • Ageing
  • Psychology(all)

Cite this

Lack of evidence for an impairment of tuberoinfundibolar dopaminergic neurons in aged male rats of the sprague-dawley strain. / Amoroso, S.; Di Renzo, G. F.; Maurano, F.; Maida, P.; Tagliatatela, M.; Annunziato, L.

In: Experimental Aging Research, Vol. 13, No. 2, 1987, p. 85-87.

Research output: Contribution to journalArticle

Amoroso, S. ; Di Renzo, G. F. ; Maurano, F. ; Maida, P. ; Tagliatatela, M. ; Annunziato, L. / Lack of evidence for an impairment of tuberoinfundibolar dopaminergic neurons in aged male rats of the sprague-dawley strain. In: Experimental Aging Research. 1987 ; Vol. 13, No. 2. pp. 85-87.
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