Abstract
Circulating prolactin (PRL) levels, dopamine (DA) content, in vitro basal and stimulus-evoked endogenous DA release from arcuate-periventricular nuclei median-eminence fragments were studied in young (4 months) and old (24-25 months) male rats of Sprague-Dawley strain. Serum PRL levels did not differ in young and aged animals. In addition DA tissue content, basal and K+- or d-amphetamine evoked endogenous DA release did not show age-related differences. These results suggest that in male rats of the Sprague-Dawley strain the activity of tuberoinfundibular dopaminergic (TIDA) neurons does not change during senescence, unlike what happens in other strains of rats.
| Original language | English |
|---|---|
| Pages (from-to) | 85-87 |
| Number of pages | 3 |
| Journal | Experimental Aging Research |
| Volume | 13 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 1987 |
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ASJC Scopus subject areas
- Geriatrics and Gerontology
- Arts and Humanities (miscellaneous)
- Ageing
- Psychology(all)
Cite this
Lack of evidence for an impairment of tuberoinfundibolar dopaminergic neurons in aged male rats of the sprague-dawley strain. / Amoroso, S.; Di Renzo, G. F.; Maurano, F.; Maida, P.; Tagliatatela, M.; Annunziato, L.
In: Experimental Aging Research, Vol. 13, No. 2, 1987, p. 85-87.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Lack of evidence for an impairment of tuberoinfundibolar dopaminergic neurons in aged male rats of the sprague-dawley strain
AU - Amoroso, S.
AU - Di Renzo, G. F.
AU - Maurano, F.
AU - Maida, P.
AU - Tagliatatela, M.
AU - Annunziato, L.
PY - 1987
Y1 - 1987
N2 - Circulating prolactin (PRL) levels, dopamine (DA) content, in vitro basal and stimulus-evoked endogenous DA release from arcuate-periventricular nuclei median-eminence fragments were studied in young (4 months) and old (24-25 months) male rats of Sprague-Dawley strain. Serum PRL levels did not differ in young and aged animals. In addition DA tissue content, basal and K+- or d-amphetamine evoked endogenous DA release did not show age-related differences. These results suggest that in male rats of the Sprague-Dawley strain the activity of tuberoinfundibular dopaminergic (TIDA) neurons does not change during senescence, unlike what happens in other strains of rats.
AB - Circulating prolactin (PRL) levels, dopamine (DA) content, in vitro basal and stimulus-evoked endogenous DA release from arcuate-periventricular nuclei median-eminence fragments were studied in young (4 months) and old (24-25 months) male rats of Sprague-Dawley strain. Serum PRL levels did not differ in young and aged animals. In addition DA tissue content, basal and K+- or d-amphetamine evoked endogenous DA release did not show age-related differences. These results suggest that in male rats of the Sprague-Dawley strain the activity of tuberoinfundibular dopaminergic (TIDA) neurons does not change during senescence, unlike what happens in other strains of rats.
UR - http://www.scopus.com/inward/record.url?scp=0023221361&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0023221361&partnerID=8YFLogxK
U2 - 10.1080/03610738708259305
DO - 10.1080/03610738708259305
M3 - Article
C2 - 3678356
AN - SCOPUS:0023221361
VL - 13
SP - 85
EP - 87
JO - Experimental Aging Research
JF - Experimental Aging Research
SN - 0361-073X
IS - 2
ER -