Lack of evidence for increased risk of hepatitis A infection in homosexual men

R. Corona, T. Stroffolini, A. Giglio, R. Cotichini, M. E. Tosti, G. Prignano, A. Di Carlo, A. Maini, A. Mele

Research output: Contribution to journalArticle

Abstract

In 1997, prevalence of and risk factors for hepatitis A virus (HAV) infection were evaluated in 146 homosexual and 286 heterosexual men attending a Sexually Transmitted Disease (STD) Clinic in Rome, Italy. Total HAV antibody (anti-HAV) was detected in 60.3% of homosexuals and 62.2% of heterosexuals. After adjustment for the confounding effects of age, years of schooling, number of sexual partners, use of condoms, and history of STD, homosexuals were not found to be at increased risk of previous HAV exposure than heterosexuals (OR 1.1; 95% CI 0.7-1.9). Independent predictors of the likelihood of anti-HAV seropositivity among homosexuals and heterosexuals were: age older than 35 years and positive syphilis serology which is likely a proxy of lifestyles that increase the risk of faecal-oral infections. These findings do not support a higher risk in homosexual men but could suggest a role for the vaccination of susceptible patients attending STD clinics.

Original languageEnglish
Pages (from-to)89-93
Number of pages5
JournalEpidemiology and Infection
Volume123
Issue number1
DOIs
Publication statusPublished - Aug 1999

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Immunology

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    Corona, R., Stroffolini, T., Giglio, A., Cotichini, R., Tosti, M. E., Prignano, G., Di Carlo, A., Maini, A., & Mele, A. (1999). Lack of evidence for increased risk of hepatitis A infection in homosexual men. Epidemiology and Infection, 123(1), 89-93. https://doi.org/10.1017/S0950268899002678