Lacosamide in pediatric and adult patients: Comparison of efficacy and safety

Alberto Verrotti, Giulia Loiacono, Antonella Pizzolorusso, Pasquale Parisi, Oliviero Bruni, Anna Luchetti, Nelia Zamponi, Silvia Cappanera, Salvatore Grosso, Gerhard Kluger, Christine Janello, Emilio Franzoni, Maurizio Elia, Alberto Spalice, Giangennaro Coppola, Pasquale Striano, Piero Pavone, Salvatore Savasta, Maurizio Viri, Antonino RomeoPaolo Aloisi, Giuseppe Gobbi, Alessandro Ferretti, Raffaella Cusmai, Paolo Curatolo

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Purpose: This multicenter, prospective study investigates the efficacy and safety of lacosamide adjunctive therapy in pediatric and adult patients with uncontrolled epilepsy. Method: This study was carried out between September 2010 and December 2011 at 16 Italian and 1 German neurologic centers. Lacosamide was added to the baseline therapy at a starting dose of 1 mg/kg/day in patients aged

Original languageEnglish
Pages (from-to)210-216
Number of pages7
JournalSeizure
Volume22
Issue number3
DOIs
Publication statusPublished - Apr 2013

Fingerprint

Pediatrics
Safety
Nervous System
Multicenter Studies
Epilepsy
Prospective Studies
Therapeutics
lacosamide

Keywords

  • Adult
  • Antiepileptic drug
  • Children
  • Efficacy
  • Epilepsy
  • Lacosamide

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Cite this

Verrotti, A., Loiacono, G., Pizzolorusso, A., Parisi, P., Bruni, O., Luchetti, A., ... Curatolo, P. (2013). Lacosamide in pediatric and adult patients: Comparison of efficacy and safety. Seizure, 22(3), 210-216. https://doi.org/10.1016/j.seizure.2012.12.009

Lacosamide in pediatric and adult patients : Comparison of efficacy and safety. / Verrotti, Alberto; Loiacono, Giulia; Pizzolorusso, Antonella; Parisi, Pasquale; Bruni, Oliviero; Luchetti, Anna; Zamponi, Nelia; Cappanera, Silvia; Grosso, Salvatore; Kluger, Gerhard; Janello, Christine; Franzoni, Emilio; Elia, Maurizio; Spalice, Alberto; Coppola, Giangennaro; Striano, Pasquale; Pavone, Piero; Savasta, Salvatore; Viri, Maurizio; Romeo, Antonino; Aloisi, Paolo; Gobbi, Giuseppe; Ferretti, Alessandro; Cusmai, Raffaella; Curatolo, Paolo.

In: Seizure, Vol. 22, No. 3, 04.2013, p. 210-216.

Research output: Contribution to journalArticle

Verrotti, A, Loiacono, G, Pizzolorusso, A, Parisi, P, Bruni, O, Luchetti, A, Zamponi, N, Cappanera, S, Grosso, S, Kluger, G, Janello, C, Franzoni, E, Elia, M, Spalice, A, Coppola, G, Striano, P, Pavone, P, Savasta, S, Viri, M, Romeo, A, Aloisi, P, Gobbi, G, Ferretti, A, Cusmai, R & Curatolo, P 2013, 'Lacosamide in pediatric and adult patients: Comparison of efficacy and safety', Seizure, vol. 22, no. 3, pp. 210-216. https://doi.org/10.1016/j.seizure.2012.12.009
Verrotti A, Loiacono G, Pizzolorusso A, Parisi P, Bruni O, Luchetti A et al. Lacosamide in pediatric and adult patients: Comparison of efficacy and safety. Seizure. 2013 Apr;22(3):210-216. https://doi.org/10.1016/j.seizure.2012.12.009
Verrotti, Alberto ; Loiacono, Giulia ; Pizzolorusso, Antonella ; Parisi, Pasquale ; Bruni, Oliviero ; Luchetti, Anna ; Zamponi, Nelia ; Cappanera, Silvia ; Grosso, Salvatore ; Kluger, Gerhard ; Janello, Christine ; Franzoni, Emilio ; Elia, Maurizio ; Spalice, Alberto ; Coppola, Giangennaro ; Striano, Pasquale ; Pavone, Piero ; Savasta, Salvatore ; Viri, Maurizio ; Romeo, Antonino ; Aloisi, Paolo ; Gobbi, Giuseppe ; Ferretti, Alessandro ; Cusmai, Raffaella ; Curatolo, Paolo. / Lacosamide in pediatric and adult patients : Comparison of efficacy and safety. In: Seizure. 2013 ; Vol. 22, No. 3. pp. 210-216.
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