Lactate and lactate clearance in acute cardiac care patients

Paola Attanà, Chiara Lazzeri, Claudio Picariello, Carlotta Sorini Dini, Gian Franco Gensini, Serafina Valente

Research output: Contribution to journalArticlepeer-review


Hyperlactataemia is commonly used as a diagnostic and prognostic tool in intensive care settings. Recent studies documented that serial lactate measurements over time (or lactate clearance), may be clinically more reliable than lactate absolute value for risk stratification in different pathological conditions. While the negative prognostic role of hyperlactataemia in several critical ill diseases (such as sepsis and trauma) is well established, data in patients with acute cardiac conditions (i.e. acute coronary syndromes) are scarce and controversial. The present paper provides an overview of the current available evidence on the clinical role of lactic acid levels and lactate clearance in acute cardiac settings (acute coronary syndromes, cardiogenic shock, cardiac surgery), focusing on its prognostic role.

Original languageEnglish
Pages (from-to)115-121
Number of pages7
JournalEuropean Heart Journal: Acute Cardiovascular Care
Issue number2
Publication statusPublished - 2012


  • Acute cardiac setting
  • lactate
  • lactate clearance

ASJC Scopus subject areas

  • Medicine(all)


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