Landau-Kleffner syndrome (LKS) is clinically characterized by acquired aphasia, auditory agnosia and seizures. EEG usually shows focal spikes and spike-waves predominantly over the temporal regions, continuous or subcontinuous during sleep. We describe two case with late onset (6,4 years and 6,8 years) with focal and generalized seizures, spike-waves predominantly over the temporal regions, continuous or subcontinuous during sleep, and neuropsychological disorders, predominantly in verbal skills. Both of them showed a dramatic clinical, EEG, and neuropsychological response to ESM, already known as one of the best pharmacological treatment for this disease. We stress the importance of early diagnosis, effective and timely treatment in order to obtain a good long-term outcome in LKS.
|Translated title of the contribution||Landau-kleffner syndrome: Clinical and neuropsychological description of two cases with onset in school age|
|Number of pages||3|
|Journal||Bollettino - Lega Italiana contro l'Epilessia|
|Publication status||Published - May 2012|
ASJC Scopus subject areas
- Clinical Neurology