Langerhans cells in the uterine cervix

S. Alberico, R. Casaccia, M. F. Facca, L. Di Bonito, G. Mandruzzato

Research output: Contribution to journalArticlepeer-review


Langerhans cells (LC) have been identified by immunoperoxidase mehtod in the native, metaplastic and dysplastic epithelium of the uterine cervix. Tissue samples were obtained from 10 patients, that underwent cervical conization for dysplasia or carcinoma in situ. The number of LC/mm2 showing OKT6 positivity was 80.42 ± 19.69 sd in the native, 31.28 ± 9.98 sd in the metaplastic, and 36.61 ± 17.17 in the dysplastic epithelium. The number of LC showing OKDR positivity were 134.33 ± 30.86 sd, 73.75 ± 7.13 sd and 51.12 ± 12.29 sd, respectively. The significance of such decrease in LC number from the normal to dysplastic epithelium is discussed.

Original languageEnglish
Pages (from-to)201-205
Number of pages5
JournalCervix and the Lower Female Genital Tract
Issue number3
Publication statusPublished - 1989

ASJC Scopus subject areas

  • Obstetrics and Gynaecology


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