Abstract
Aim. The primary objective of the study-was to compare the effect of laparoscopic-assisted (LPS) versus open surgery (LPT) for colorectal cancer on postoperative morbidity. The secondary objectives were to evaluate immune response and intestinal wall oxygen perfusion. Methods. A total of 610 patients with colorectal cancer were randomly assigned to receive colon resection by either LPS (n=306) or LPT (n=304). Four surgical staff members not involved in the study recorded postoperative complications up to 30 days after the operation. Immune response was evaluated by measuring lymphocytic proliferation after challenge with Candida albicans and phytohemoagglutinin before, at 3 and 15 days after the operation. Intestinal wall oxygen perfusion was continuously monitored using a probe. Results. The conversion rate was 4.6% in the LPS group. Morbidity was 18.6% in the LPS group and 34.5% in the LPT group (P
Translated title of the contribution | Laparoscopic-assisted versus open surgery for colorectal cancer: Postoperative morbidity in a single center randomized trial |
---|---|
Original language | Italian |
Pages (from-to) | 283-292 |
Number of pages | 10 |
Journal | Minerva Chirurgica |
Volume | 61 |
Issue number | 4 |
Publication status | Published - Aug 2006 |
ASJC Scopus subject areas
- Surgery