Laparoscopia vs approccio aperto in chirurgia colorettale: Morbidità postoperatoria in un trial randomizzato monocentrico

Translated title of the contribution: Laparoscopic-assisted versus open surgery for colorectal cancer: Postoperative morbidity in a single center randomized trial

M. Frasson, M. Braga, A. Vignali, W. Zuliani, P. Gruarin, P. Dellabona, V. Di Carlo

Research output: Contribution to journalArticle

Abstract

Aim. The primary objective of the study-was to compare the effect of laparoscopic-assisted (LPS) versus open surgery (LPT) for colorectal cancer on postoperative morbidity. The secondary objectives were to evaluate immune response and intestinal wall oxygen perfusion. Methods. A total of 610 patients with colorectal cancer were randomly assigned to receive colon resection by either LPS (n=306) or LPT (n=304). Four surgical staff members not involved in the study recorded postoperative complications up to 30 days after the operation. Immune response was evaluated by measuring lymphocytic proliferation after challenge with Candida albicans and phytohemoagglutinin before, at 3 and 15 days after the operation. Intestinal wall oxygen perfusion was continuously monitored using a probe. Results. The conversion rate was 4.6% in the LPS group. Morbidity was 18.6% in the LPS group and 34.5% in the LPT group (P

Original languageItalian
Pages (from-to)283-292
Number of pages10
JournalMinerva Chirurgica
Volume61
Issue number4
Publication statusPublished - Aug 2006

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Colorectal Neoplasms
Perfusion
Oxygen
Morbidity
Candida albicans
Colon

ASJC Scopus subject areas

  • Surgery

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Laparoscopia vs approccio aperto in chirurgia colorettale : Morbidità postoperatoria in un trial randomizzato monocentrico. / Frasson, M.; Braga, M.; Vignali, A.; Zuliani, W.; Gruarin, P.; Dellabona, P.; Di Carlo, V.

In: Minerva Chirurgica, Vol. 61, No. 4, 08.2006, p. 283-292.

Research output: Contribution to journalArticle

Frasson, M. ; Braga, M. ; Vignali, A. ; Zuliani, W. ; Gruarin, P. ; Dellabona, P. ; Di Carlo, V. / Laparoscopia vs approccio aperto in chirurgia colorettale : Morbidità postoperatoria in un trial randomizzato monocentrico. In: Minerva Chirurgica. 2006 ; Vol. 61, No. 4. pp. 283-292.
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AU - Vignali, A.

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AU - Gruarin, P.

AU - Dellabona, P.

AU - Di Carlo, V.

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