Abstract
Aim. The primary objective of the study-was to compare the effect of laparoscopic-assisted (LPS) versus open surgery (LPT) for colorectal cancer on postoperative morbidity. The secondary objectives were to evaluate immune response and intestinal wall oxygen perfusion. Methods. A total of 610 patients with colorectal cancer were randomly assigned to receive colon resection by either LPS (n=306) or LPT (n=304). Four surgical staff members not involved in the study recorded postoperative complications up to 30 days after the operation. Immune response was evaluated by measuring lymphocytic proliferation after challenge with Candida albicans and phytohemoagglutinin before, at 3 and 15 days after the operation. Intestinal wall oxygen perfusion was continuously monitored using a probe. Results. The conversion rate was 4.6% in the LPS group. Morbidity was 18.6% in the LPS group and 34.5% in the LPT group (P
| Original language | Italian |
|---|---|
| Pages (from-to) | 283-292 |
| Number of pages | 10 |
| Journal | Minerva Chirurgica |
| Volume | 61 |
| Issue number | 4 |
| Publication status | Published - Aug 2006 |
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ASJC Scopus subject areas
- Surgery
Cite this
Laparoscopia vs approccio aperto in chirurgia colorettale : Morbidità postoperatoria in un trial randomizzato monocentrico. / Frasson, M.; Braga, M.; Vignali, A.; Zuliani, W.; Gruarin, P.; Dellabona, P.; Di Carlo, V.
In: Minerva Chirurgica, Vol. 61, No. 4, 08.2006, p. 283-292.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Laparoscopia vs approccio aperto in chirurgia colorettale
T2 - Morbidità postoperatoria in un trial randomizzato monocentrico
AU - Frasson, M.
AU - Braga, M.
AU - Vignali, A.
AU - Zuliani, W.
AU - Gruarin, P.
AU - Dellabona, P.
AU - Di Carlo, V.
PY - 2006/8
Y1 - 2006/8
N2 - Aim. The primary objective of the study-was to compare the effect of laparoscopic-assisted (LPS) versus open surgery (LPT) for colorectal cancer on postoperative morbidity. The secondary objectives were to evaluate immune response and intestinal wall oxygen perfusion. Methods. A total of 610 patients with colorectal cancer were randomly assigned to receive colon resection by either LPS (n=306) or LPT (n=304). Four surgical staff members not involved in the study recorded postoperative complications up to 30 days after the operation. Immune response was evaluated by measuring lymphocytic proliferation after challenge with Candida albicans and phytohemoagglutinin before, at 3 and 15 days after the operation. Intestinal wall oxygen perfusion was continuously monitored using a probe. Results. The conversion rate was 4.6% in the LPS group. Morbidity was 18.6% in the LPS group and 34.5% in the LPT group (P
AB - Aim. The primary objective of the study-was to compare the effect of laparoscopic-assisted (LPS) versus open surgery (LPT) for colorectal cancer on postoperative morbidity. The secondary objectives were to evaluate immune response and intestinal wall oxygen perfusion. Methods. A total of 610 patients with colorectal cancer were randomly assigned to receive colon resection by either LPS (n=306) or LPT (n=304). Four surgical staff members not involved in the study recorded postoperative complications up to 30 days after the operation. Immune response was evaluated by measuring lymphocytic proliferation after challenge with Candida albicans and phytohemoagglutinin before, at 3 and 15 days after the operation. Intestinal wall oxygen perfusion was continuously monitored using a probe. Results. The conversion rate was 4.6% in the LPS group. Morbidity was 18.6% in the LPS group and 34.5% in the LPT group (P
KW - Colonic neoplasms, surgery
KW - Laparoscopy
KW - Oxigen tension
KW - Postoperative complications
KW - Rectal neoplasms, surgery
UR - http://www.scopus.com/inward/record.url?scp=33846509875&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33846509875&partnerID=8YFLogxK
M3 - Articolo
C2 - 17122760
AN - SCOPUS:33846509875
VL - 61
SP - 283
EP - 292
JO - Minerva Chirurgica
JF - Minerva Chirurgica
SN - 0026-4733
IS - 4
ER -