Laparoscopic colorectal surgery modifies risk factors for postoperative morbidity

Andrea Vignali, Marco Braga, Walter Zuliani, Matteo Frasson, Giovanni Radaelli, Valerio Di Carlo

Research output: Contribution to journalArticle

Abstract

PURPOSE: The aim of this study was to evaluate whether laparoscopic colorectal surgery can modify the risk factors for the occurrence of postoperative morbidity. METHODS: A total of 384 consecutive patients with colorectal disease were randomized to laparoscopic resection (n = 190) or open resection (n = 194). On admission, demographics, comorbidity, and nutritional status were recorded. Operative variables, patient outcome, and length of stay were also recorded. Postoperative complications were registered by four members of staff not involved in the study. RESULTS: The overall morbidity rate was 27.1 percent, with the rate in the laparoscopic group (18.7 percent) being less than that in the open group (31.5 percent; P = 0.003). Patients who underwent laparoscopic resection had a faster recovery of bowel function (P = 0.0001) and a shorter length of stay (P = 0.0001). In the whole cohort of patients, multi variate analysis identified open surgery (P = 0.003), duration of surgery (P = 0.01), and homologous blood transfusion (P = 0.01) as risk factors for postoperative morbidity. In the open group, blood loss (P = 0.01), homologous blood transfusion (P = 0.01), duration of surgery (P = 0.009), weight loss (P = 0.06), and age (P = 0.08) were related to postoperative morbidity. In the laparoscopic group the only risk factor identified was duration of surgery (P = 0.005). CONCLUSION: In the laparoscopic group, both postoperative morbidity and length of stay were significantly reduced and most risk factors for postoperative morbidity disappeared.

Original languageEnglish
Pages (from-to)1686-1693
Number of pages8
JournalDiseases of the Colon and Rectum
Volume47
Issue number10
DOIs
Publication statusPublished - Oct 2004

Fingerprint

Colorectal Surgery
Laparoscopy
Morbidity
Length of Stay
Blood Transfusion
Recovery of Function
Nutritional Status
Comorbidity
Weight Loss
Demography

Keywords

  • Colorectal cancer
  • Colorectal surgery
  • Laparoscopy
  • Postoperative complications

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Laparoscopic colorectal surgery modifies risk factors for postoperative morbidity. / Vignali, Andrea; Braga, Marco; Zuliani, Walter; Frasson, Matteo; Radaelli, Giovanni; Di Carlo, Valerio.

In: Diseases of the Colon and Rectum, Vol. 47, No. 10, 10.2004, p. 1686-1693.

Research output: Contribution to journalArticle

Vignali, Andrea ; Braga, Marco ; Zuliani, Walter ; Frasson, Matteo ; Radaelli, Giovanni ; Di Carlo, Valerio. / Laparoscopic colorectal surgery modifies risk factors for postoperative morbidity. In: Diseases of the Colon and Rectum. 2004 ; Vol. 47, No. 10. pp. 1686-1693.
@article{136af47d380c481b8dc81f2f5444175f,
title = "Laparoscopic colorectal surgery modifies risk factors for postoperative morbidity",
abstract = "PURPOSE: The aim of this study was to evaluate whether laparoscopic colorectal surgery can modify the risk factors for the occurrence of postoperative morbidity. METHODS: A total of 384 consecutive patients with colorectal disease were randomized to laparoscopic resection (n = 190) or open resection (n = 194). On admission, demographics, comorbidity, and nutritional status were recorded. Operative variables, patient outcome, and length of stay were also recorded. Postoperative complications were registered by four members of staff not involved in the study. RESULTS: The overall morbidity rate was 27.1 percent, with the rate in the laparoscopic group (18.7 percent) being less than that in the open group (31.5 percent; P = 0.003). Patients who underwent laparoscopic resection had a faster recovery of bowel function (P = 0.0001) and a shorter length of stay (P = 0.0001). In the whole cohort of patients, multi variate analysis identified open surgery (P = 0.003), duration of surgery (P = 0.01), and homologous blood transfusion (P = 0.01) as risk factors for postoperative morbidity. In the open group, blood loss (P = 0.01), homologous blood transfusion (P = 0.01), duration of surgery (P = 0.009), weight loss (P = 0.06), and age (P = 0.08) were related to postoperative morbidity. In the laparoscopic group the only risk factor identified was duration of surgery (P = 0.005). CONCLUSION: In the laparoscopic group, both postoperative morbidity and length of stay were significantly reduced and most risk factors for postoperative morbidity disappeared.",
keywords = "Colorectal cancer, Colorectal surgery, Laparoscopy, Postoperative complications",
author = "Andrea Vignali and Marco Braga and Walter Zuliani and Matteo Frasson and Giovanni Radaelli and {Di Carlo}, Valerio",
year = "2004",
month = "10",
doi = "10.1007/s10350-004-0653-5",
language = "English",
volume = "47",
pages = "1686--1693",
journal = "Diseases of the Colon and Rectum",
issn = "0012-3706",
publisher = "Lippincott Williams and Wilkins",
number = "10",

}

TY - JOUR

T1 - Laparoscopic colorectal surgery modifies risk factors for postoperative morbidity

AU - Vignali, Andrea

AU - Braga, Marco

AU - Zuliani, Walter

AU - Frasson, Matteo

AU - Radaelli, Giovanni

AU - Di Carlo, Valerio

PY - 2004/10

Y1 - 2004/10

N2 - PURPOSE: The aim of this study was to evaluate whether laparoscopic colorectal surgery can modify the risk factors for the occurrence of postoperative morbidity. METHODS: A total of 384 consecutive patients with colorectal disease were randomized to laparoscopic resection (n = 190) or open resection (n = 194). On admission, demographics, comorbidity, and nutritional status were recorded. Operative variables, patient outcome, and length of stay were also recorded. Postoperative complications were registered by four members of staff not involved in the study. RESULTS: The overall morbidity rate was 27.1 percent, with the rate in the laparoscopic group (18.7 percent) being less than that in the open group (31.5 percent; P = 0.003). Patients who underwent laparoscopic resection had a faster recovery of bowel function (P = 0.0001) and a shorter length of stay (P = 0.0001). In the whole cohort of patients, multi variate analysis identified open surgery (P = 0.003), duration of surgery (P = 0.01), and homologous blood transfusion (P = 0.01) as risk factors for postoperative morbidity. In the open group, blood loss (P = 0.01), homologous blood transfusion (P = 0.01), duration of surgery (P = 0.009), weight loss (P = 0.06), and age (P = 0.08) were related to postoperative morbidity. In the laparoscopic group the only risk factor identified was duration of surgery (P = 0.005). CONCLUSION: In the laparoscopic group, both postoperative morbidity and length of stay were significantly reduced and most risk factors for postoperative morbidity disappeared.

AB - PURPOSE: The aim of this study was to evaluate whether laparoscopic colorectal surgery can modify the risk factors for the occurrence of postoperative morbidity. METHODS: A total of 384 consecutive patients with colorectal disease were randomized to laparoscopic resection (n = 190) or open resection (n = 194). On admission, demographics, comorbidity, and nutritional status were recorded. Operative variables, patient outcome, and length of stay were also recorded. Postoperative complications were registered by four members of staff not involved in the study. RESULTS: The overall morbidity rate was 27.1 percent, with the rate in the laparoscopic group (18.7 percent) being less than that in the open group (31.5 percent; P = 0.003). Patients who underwent laparoscopic resection had a faster recovery of bowel function (P = 0.0001) and a shorter length of stay (P = 0.0001). In the whole cohort of patients, multi variate analysis identified open surgery (P = 0.003), duration of surgery (P = 0.01), and homologous blood transfusion (P = 0.01) as risk factors for postoperative morbidity. In the open group, blood loss (P = 0.01), homologous blood transfusion (P = 0.01), duration of surgery (P = 0.009), weight loss (P = 0.06), and age (P = 0.08) were related to postoperative morbidity. In the laparoscopic group the only risk factor identified was duration of surgery (P = 0.005). CONCLUSION: In the laparoscopic group, both postoperative morbidity and length of stay were significantly reduced and most risk factors for postoperative morbidity disappeared.

KW - Colorectal cancer

KW - Colorectal surgery

KW - Laparoscopy

KW - Postoperative complications

UR - http://www.scopus.com/inward/record.url?scp=4944252176&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=4944252176&partnerID=8YFLogxK

U2 - 10.1007/s10350-004-0653-5

DO - 10.1007/s10350-004-0653-5

M3 - Article

C2 - 15540300

AN - SCOPUS:4944252176

VL - 47

SP - 1686

EP - 1693

JO - Diseases of the Colon and Rectum

JF - Diseases of the Colon and Rectum

SN - 0012-3706

IS - 10

ER -