Laparoscopic colorectal surgery modifies risk factors for postoperative morbidity

Andrea Vignali, Marco Braga, Walter Zuliani, Matteo Frasson, Giovanni Radaelli, Valerio Di Carlo

Research output: Contribution to journalArticlepeer-review


PURPOSE: The aim of this study was to evaluate whether laparoscopic colorectal surgery can modify the risk factors for the occurrence of postoperative morbidity. METHODS: A total of 384 consecutive patients with colorectal disease were randomized to laparoscopic resection (n = 190) or open resection (n = 194). On admission, demographics, comorbidity, and nutritional status were recorded. Operative variables, patient outcome, and length of stay were also recorded. Postoperative complications were registered by four members of staff not involved in the study. RESULTS: The overall morbidity rate was 27.1 percent, with the rate in the laparoscopic group (18.7 percent) being less than that in the open group (31.5 percent; P = 0.003). Patients who underwent laparoscopic resection had a faster recovery of bowel function (P = 0.0001) and a shorter length of stay (P = 0.0001). In the whole cohort of patients, multi variate analysis identified open surgery (P = 0.003), duration of surgery (P = 0.01), and homologous blood transfusion (P = 0.01) as risk factors for postoperative morbidity. In the open group, blood loss (P = 0.01), homologous blood transfusion (P = 0.01), duration of surgery (P = 0.009), weight loss (P = 0.06), and age (P = 0.08) were related to postoperative morbidity. In the laparoscopic group the only risk factor identified was duration of surgery (P = 0.005). CONCLUSION: In the laparoscopic group, both postoperative morbidity and length of stay were significantly reduced and most risk factors for postoperative morbidity disappeared.

Original languageEnglish
Pages (from-to)1686-1693
Number of pages8
JournalDiseases of the Colon and Rectum
Issue number10
Publication statusPublished - Oct 2004


  • Colorectal cancer
  • Colorectal surgery
  • Laparoscopy
  • Postoperative complications

ASJC Scopus subject areas

  • Gastroenterology


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