Laparoscopic excision of recurrent endometriomas: Long-term outcome and comparison with primary surgery

Luigi Fedele, Stefano Bianchi, Giovanni Zanconato, Nicola Berlanda, Ricciarda Raffaelli, Eleonora Fontana

Research output: Contribution to journalArticlepeer-review


Objective: To compare the laparoscopic excision of primary versus recurrent ovarian endometriomas. Design: Descriptive study. Setting: Tertiary referral center for the treatment of endometriosis. Patient(s): Between 1993 and 2002, 359 consecutive patients: 305 primary surgeries (group A) and 54 reoperations for a recurrent endometrioma in the same ovary of the primary cyst (group B). Intervention(s): Laparoscopic stripping of the cyst wall. Follow-up evaluations every 6 months, including clinical and ultrasonographic evaluations and a questionnaire for pain symptoms (mean follow-up time, ± standard deviation: 35.4 ± 27.6 months). Main Outcome Measure(s): Recurrence of pain symptoms, sonographic recurrence of endometriomas, need for a new medical or surgical treatment, and reproductive outcome. Result(s): In groups A and B, respectively, the 5-year cumulative rates were not statistically significantly different: pain recurrence 20.5% versus 17.4%; ultrasonographic recurrence 18.9% versus 15.1%; retreatment requirement 19.4% versus 17.3%; and pregnancy 40.8% versus 32.4%. Although the difference was not statistically significant, compared with patients of group A, the women of group B underwent assisted reproduction techniques more frequently (50% vs. 32.2%) and had more irregular menstrual cycles associated with follicle-stimulating hormone levels ≥ 14 IU/mL in the early follicular phase (5.5% vs. 1.3%). Conclusion(s): After laparoscopic excision of recurrent ovarian endometriomas, the recurrence of pain and the reproductive outcome are comparable with those found after primary surgery.

Original languageEnglish
Pages (from-to)694-699
Number of pages6
JournalFertility and Sterility
Issue number3
Publication statusPublished - Mar 2006


  • Endometriosis
  • Ovarian cysts
  • Ovarian endometrioma
  • Recurrent endometriosis

ASJC Scopus subject areas

  • Obstetrics and Gynaecology


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