Laparoscopic "single knot-single running" suture vesico-urethral anastomosis with posterior musculofascial reconstruction

Giuseppe Simone, Rocco Papalia, Mariaconsiglia Ferriero, Salvatore Guaglianone, Michele Gallucci

Research output: Contribution to journalArticlepeer-review


Purpose: To describe results of a simplified technique to configure the vesicourethral anastomosis and to restore posterior musculofascial plate during laparoscopic radical prostatectomy with a "single knot-single running" suture. Methods: Between December 2006 and 2009, a conventional Van Velthoven anastomosis (group A) was applied in 125 cases while the novel anastomosis was applied in 155 consecutive patients (group B). A between group comparison of continence recovery was performed with log-rank test and Chi-square test. Continuous variables were compared with Wilcoxon's test and categorical ones with Chi-square test. Results: Median operative time and median time to configure the anastomosis were comparable between two groups. Proportions of patients using 0 pad, 1 pad and >1 pad per day were statistically different between groups at 1 month (54.4%, 14.4%, 31. 2% vs. 52.3%, 27.7%, 20%, in group A and group B, respectively; p = 0.01), at 3 months (73.6%, 8.8%, 17.6% vs. 86.5%, 7.1%, 6.5%; p = 0.01) and at 6 months (80.8%, 12.8%, 6.4% vs. 92.3%, 6.5%, 1.2%; p = 0.01). At log-rank test, continence recovery between two groups was statistically different (p = 0.008). Conclusions: The excellent outcome together with the easiness of performing this novel anastomosis compared to the traditional Van Velthoven make it widely reproducible.

Original languageEnglish
Pages (from-to)651-657
Number of pages7
JournalWorld Journal of Urology
Issue number5
Publication statusPublished - Nov 2012


  • Anastomosis
  • Continence
  • Laparoscopy
  • Radical prostatectomy

ASJC Scopus subject areas

  • Urology


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