Abstract
Objective: To assess and compare the laparoscopic uterine nerve ablation (LUNA) and the vaginal uterosacral ligament resection (VUSR) in postmenopausal women with chronic pelvic pain (CPP). Study design: Eighty postmenopausal women with intractable and severe midline CPP were randomized to undergo LUNA or VUSR. Costs of two surgical procedures were assesses. Cure rate, severity of CPP, and deep dyspareunia were also evaluated after 6 and 12 months from surgery. Results: The mean cost of LUNA resulted significantly higher in comparison with VURS (2078 ± 637 versus 1497 ± 297, P <0.001). The cure rate was not significantly different between the two groups at 6 (33/40, 82.5% versus 35/40, 87.5% for groups A and B, respectively; P = 0.530; RR 0.94, 95% CI 0.78-1.13), and 12 months (27/36, 75.0% versus 28/38, 73.7%, for groups A and B, respectively; P = 0.901; RR 0.90, 95% CI 0.78-1.33) of follow-up. At same times, a significant (P <0.01) decrease in severity of CPP and deep dyspareunia was observed in both groups with no difference between them. Conclusions: Both LUNA and VUSR are equally effective surgical treatments in postmenopausal women with central CPP but VUNR is significantly cheaper than LUNA.
| Original language | English |
|---|---|
| Pages (from-to) | 84-91 |
| Number of pages | 8 |
| Journal | European Journal of Obstetrics and Gynecology and Reproductive Biology |
| Volume | 129 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Nov 2006 |
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Keywords
- Chronic pelvic pain
- Laparoscopic uterine nerve ablation
- LUNA
- Pelvic denervation
- Uterosacral ligament resection
ASJC Scopus subject areas
- Obstetrics and Gynaecology
- Reproductive Medicine
Cite this
Laparoscopic uterine nerve ablation versus vaginal uterosacral ligament resection in postmenopausal women with intractable midline chronic pelvic pain : A randomized study. / Palomba, Stefano; Russo, Tiziana; Falbo, Angela; Manguso, Francesco; D'Alessandro, Pietro; Mattei, Alberto; Tolino, Achille; Branconi, Francesco; Zupi, Errico; Zullo, Fulvio.
In: European Journal of Obstetrics and Gynecology and Reproductive Biology, Vol. 129, No. 1, 11.2006, p. 84-91.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Laparoscopic uterine nerve ablation versus vaginal uterosacral ligament resection in postmenopausal women with intractable midline chronic pelvic pain
T2 - A randomized study
AU - Palomba, Stefano
AU - Russo, Tiziana
AU - Falbo, Angela
AU - Manguso, Francesco
AU - D'Alessandro, Pietro
AU - Mattei, Alberto
AU - Tolino, Achille
AU - Branconi, Francesco
AU - Zupi, Errico
AU - Zullo, Fulvio
PY - 2006/11
Y1 - 2006/11
N2 - Objective: To assess and compare the laparoscopic uterine nerve ablation (LUNA) and the vaginal uterosacral ligament resection (VUSR) in postmenopausal women with chronic pelvic pain (CPP). Study design: Eighty postmenopausal women with intractable and severe midline CPP were randomized to undergo LUNA or VUSR. Costs of two surgical procedures were assesses. Cure rate, severity of CPP, and deep dyspareunia were also evaluated after 6 and 12 months from surgery. Results: The mean cost of LUNA resulted significantly higher in comparison with VURS (2078 ± 637 versus 1497 ± 297, P <0.001). The cure rate was not significantly different between the two groups at 6 (33/40, 82.5% versus 35/40, 87.5% for groups A and B, respectively; P = 0.530; RR 0.94, 95% CI 0.78-1.13), and 12 months (27/36, 75.0% versus 28/38, 73.7%, for groups A and B, respectively; P = 0.901; RR 0.90, 95% CI 0.78-1.33) of follow-up. At same times, a significant (P <0.01) decrease in severity of CPP and deep dyspareunia was observed in both groups with no difference between them. Conclusions: Both LUNA and VUSR are equally effective surgical treatments in postmenopausal women with central CPP but VUNR is significantly cheaper than LUNA.
AB - Objective: To assess and compare the laparoscopic uterine nerve ablation (LUNA) and the vaginal uterosacral ligament resection (VUSR) in postmenopausal women with chronic pelvic pain (CPP). Study design: Eighty postmenopausal women with intractable and severe midline CPP were randomized to undergo LUNA or VUSR. Costs of two surgical procedures were assesses. Cure rate, severity of CPP, and deep dyspareunia were also evaluated after 6 and 12 months from surgery. Results: The mean cost of LUNA resulted significantly higher in comparison with VURS (2078 ± 637 versus 1497 ± 297, P <0.001). The cure rate was not significantly different between the two groups at 6 (33/40, 82.5% versus 35/40, 87.5% for groups A and B, respectively; P = 0.530; RR 0.94, 95% CI 0.78-1.13), and 12 months (27/36, 75.0% versus 28/38, 73.7%, for groups A and B, respectively; P = 0.901; RR 0.90, 95% CI 0.78-1.33) of follow-up. At same times, a significant (P <0.01) decrease in severity of CPP and deep dyspareunia was observed in both groups with no difference between them. Conclusions: Both LUNA and VUSR are equally effective surgical treatments in postmenopausal women with central CPP but VUNR is significantly cheaper than LUNA.
KW - Chronic pelvic pain
KW - Laparoscopic uterine nerve ablation
KW - LUNA
KW - Pelvic denervation
KW - Uterosacral ligament resection
UR - http://www.scopus.com/inward/record.url?scp=33750346756&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33750346756&partnerID=8YFLogxK
U2 - 10.1016/j.ejogrb.2005.12.007
DO - 10.1016/j.ejogrb.2005.12.007
M3 - Article
C2 - 16442203
AN - SCOPUS:33750346756
VL - 129
SP - 84
EP - 91
JO - European Journal of Obstetrics, Gynecology and Reproductive Biology
JF - European Journal of Obstetrics, Gynecology and Reproductive Biology
SN - 0028-2243
IS - 1
ER -