Abstract
Objective. To investigate in depth the effect of increasing age on the peri-operative outcomes of laparoscopic treatment for endometrial cancer, compared to open surgery, with stratification of patients according to the different definitions of elderly age used in the literature. Methods: Data of consecutive patients who underwent surgery for endometrial cancer staging at six centers were reviewed and analyzed according to surgical approach (laparoscopic or open), different definitions of elderly and very elderly age (≥. 65. years, ≥. 75. years, ≥. 80. years), and class of age (. 0.05). The same tendency was observed among very-elderly patients (≥. 80. years). Multivariable and propensity score-matched analysis confirmed these findings. Conclusions: Laparoscopy for staging endometrial cancer retains its advantages over open surgery even in elderly and very-elderly patients. Our data strongly suggest that minimally-invasive surgery is advantageous even among subjects ≥. 80. years.
| Original language | English |
|---|---|
| Journal | Gynecologic Oncology |
| DOIs | |
| Publication status | Accepted/In press - Feb 5 2016 |
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Keywords
- Aging
- Elderly
- Endometrial cancer
- Laparoscopy
- Minimally-invasive
- Surgery
ASJC Scopus subject areas
- Obstetrics and Gynaecology
- Oncology
Cite this
Laparoscopic vs. open treatment of endometrial cancer in the elderly and very elderly : An age-stratified multicenter study on 1606 women. / Uccella, Stefano; Bonzini, Matteo; Palomba, Stefano; Fanfani, Francesco; Malzoni, Mario; Ceccaroni, Marcello; Seracchioli, Renato; Ferrero, Annamaria; Berretta, Roberto; Vizza, Enrico; Sturla, Davide; Roviglione, Giovanni; Monterossi, Giorgia; Casadio, Paolo; Volpi, Eugenio; Mautone, Daniele; Corrado, Giacomo; Bruni, Francesco; Scambia, Giovanni; Ghezzi, Fabio.
In: Gynecologic Oncology, 05.02.2016.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Laparoscopic vs. open treatment of endometrial cancer in the elderly and very elderly
T2 - An age-stratified multicenter study on 1606 women
AU - Uccella, Stefano
AU - Bonzini, Matteo
AU - Palomba, Stefano
AU - Fanfani, Francesco
AU - Malzoni, Mario
AU - Ceccaroni, Marcello
AU - Seracchioli, Renato
AU - Ferrero, Annamaria
AU - Berretta, Roberto
AU - Vizza, Enrico
AU - Sturla, Davide
AU - Roviglione, Giovanni
AU - Monterossi, Giorgia
AU - Casadio, Paolo
AU - Volpi, Eugenio
AU - Mautone, Daniele
AU - Corrado, Giacomo
AU - Bruni, Francesco
AU - Scambia, Giovanni
AU - Ghezzi, Fabio
PY - 2016/2/5
Y1 - 2016/2/5
N2 - Objective. To investigate in depth the effect of increasing age on the peri-operative outcomes of laparoscopic treatment for endometrial cancer, compared to open surgery, with stratification of patients according to the different definitions of elderly age used in the literature. Methods: Data of consecutive patients who underwent surgery for endometrial cancer staging at six centers were reviewed and analyzed according to surgical approach (laparoscopic or open), different definitions of elderly and very elderly age (≥. 65. years, ≥. 75. years, ≥. 80. years), and class of age (. 0.05). The same tendency was observed among very-elderly patients (≥. 80. years). Multivariable and propensity score-matched analysis confirmed these findings. Conclusions: Laparoscopy for staging endometrial cancer retains its advantages over open surgery even in elderly and very-elderly patients. Our data strongly suggest that minimally-invasive surgery is advantageous even among subjects ≥. 80. years.
AB - Objective. To investigate in depth the effect of increasing age on the peri-operative outcomes of laparoscopic treatment for endometrial cancer, compared to open surgery, with stratification of patients according to the different definitions of elderly age used in the literature. Methods: Data of consecutive patients who underwent surgery for endometrial cancer staging at six centers were reviewed and analyzed according to surgical approach (laparoscopic or open), different definitions of elderly and very elderly age (≥. 65. years, ≥. 75. years, ≥. 80. years), and class of age (. 0.05). The same tendency was observed among very-elderly patients (≥. 80. years). Multivariable and propensity score-matched analysis confirmed these findings. Conclusions: Laparoscopy for staging endometrial cancer retains its advantages over open surgery even in elderly and very-elderly patients. Our data strongly suggest that minimally-invasive surgery is advantageous even among subjects ≥. 80. years.
KW - Aging
KW - Elderly
KW - Endometrial cancer
KW - Laparoscopy
KW - Minimally-invasive
KW - Surgery
UR - http://www.scopus.com/inward/record.url?scp=84959255005&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84959255005&partnerID=8YFLogxK
U2 - 10.1016/j.ygyno.2016.02.029
DO - 10.1016/j.ygyno.2016.02.029
M3 - Article
AN - SCOPUS:84959255005
JO - Gynecologic Oncology
JF - Gynecologic Oncology
SN - 0090-8258
ER -