Large choroidal excavation in retinitis pigmentosa: A case report

Pierluigi Iacono, Maurizio Battaglia Parodi, Mariacristina Parravano, Monica Varano

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: To report the morphological and clinical features of a case of retinitis pigmentosa with large choroidal excavation. Methods: The patient underwent a complete ophthalmologic examination including best-corrected visual acuity assessment, anterior segment and dilated fundus examination and spectral-domain optical coherence tomography. Results: A 41-year-old woman affected by retinitis pigmentosa with genetic confirmation with mutation in RDH12 gene had a best-corrected visual acuity of 20/50 in both eyes. Dilated fundus examination revealed waxy pallor of the optic disc, diffuse narrowing of the retinal arterioles and a generalized retinal pigment epithelium mottling with bony spicule associated with diffuse retinal atrophy. At the posterior pole, an extended bilateral chorioretinal atrophy was evident with a partial sparing of the macular area. On spectral-domain optical coherence tomography, a bilateral large choroidal excavation could be clearly detected and it was associated with a diffuse retinal thinning at the posterior pole and a partial sparing of the fovea. Conclusion: Large choroidal excavation has been rarely reported. Although the pathogenetic mechanisms leading to the formation of large choroidal excavation are still a matter of debate, a combination of primary degenerative-inflammatory factors could be retained responsible for the large choroidal excavation development.

Original languageEnglish
JournalEuropean Journal of Ophthalmology
DOIs
Publication statusE-pub ahead of print - Dec 4 2019

Keywords

  • Large choroidal excavation
  • retinitis pigmentosa

ASJC Scopus subject areas

  • Ophthalmology

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