Laryngeal lymphoma derived from mucosa-associated lymphoid tissue

Alfio Ferlito, Hans Peter Horny, Antonino Carbone

Research output: Contribution to journalArticlepeer-review


Extranodal lymphomas account for as many as 40% of non-Hodgkin's lymphomas, and most arise in the gastrointestinal tract, but other mucosal organs may be involved, especially the upper aerodigestive tract. Low-grade B-cell lymphomas arising in the gastrointestinal tract and other mucosae have been found to recapitulate the structure and cytologic features of mucosa- associated lymphoid tissue (MALT). Histologically low-grade MALT lymphomas are characterized by centrocyte-like B-cells with a phenotype similar to that of so-called marginal zone B-cells. Tumors evolving from MALT are generally rare among lymphomas of the upper aerodigestive tract, but a few cases of laryngeal lymphomas derived from MALT have been reported. Primary MALT lymphoma of the larynx should always be considered in tumors with histopathologic features of low-grade B-cell lymphoma, or so-called pseudolymphoma.

Original languageEnglish
Pages (from-to)577-583
Number of pages7
JournalAnnals of Otology, Rhinology and Laryngology
Issue number7
Publication statusPublished - 1996

ASJC Scopus subject areas

  • Otorhinolaryngology


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