Late (Complicated) Parkinson's Disease

W. H. Oertel, A. Berardelli, B. R. Bloem, U. Bonuccelli, D. Burn, G. Deuschl, E. Dietrichs, G. Fabbrini, J. J. Ferreira, A. Friedman, P. Kanovsky, V. Kostic, A. Nieuwboer, P. Odin, W. Poewe, O. Rascol, C. Sampaio, M. Schüpbach, E. Tolosa, C. Trenkwalder

Research output: Chapter in Book/Report/Conference proceedingChapter

Original languageEnglish
Title of host publicationEuropean Handbook of Neurological Management: Second Edition
Number of pages31
ISBN (Print)9781405185332
Publication statusPublished - Sep 6 2010


  • Alternative levodopa formulations and delivery routes
  • Biphasic dyskinesias, difficult to treat-have not been subject of specific and adequate Class I-III studies
  • Cued gait training in home-probably effective in reducing severity of freezing of gait
  • European Agency for Evaluation of Medicinal Products (EMEA)
  • Late (complicated) Parkinson's disease
  • Levodopa-Immediate release (standard)-most important component of pharmacotherapy in advanced PD
  • Motor complications, divided into motor fluctuations and dyskinesia
  • Patients with advanced Parkinson's disease (PD)-suffering from any combination of motor and non-motor problems
  • Significant sleep disorders-being common in PD
  • Stimulation of posteroventral pallidum

ASJC Scopus subject areas

  • Neuroscience(all)

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