Late occlusive in-stent restenosis of a bare-metal stent presenting with ST-elevation anterior MI: Is restenosis better than a late stent thrombosis?

Research output: Contribution to journalArticle

Abstract

In-stent restenosis (ISR) occurs in 20% to 40% of de novo coronary lesions treated with bare-metal stents (BMS), depending on lesion and patient-related factors. Drug-eluting stents coated with antiproliferative agents, represent a valid rationale for treatment and prevention of recurrent ISR, with low MACE rates. However, case reports and observational studies reported a definite increase in the incidence of late stent thrombosis after drug-eluting stents use, particularly in off-label cases and after clopidogrel withdrawal. The case we present shows target vessel occlusion occurring at the site of a previously implanted BMS, suggesting that in-stent restenosis was the main pathological mechanism leading to abrupt thrombotic vessel closure and acute myocardial infarction.

Original languageEnglish
JournalInternational Journal of Cardiology
Volume135
Issue number2
DOIs
Publication statusPublished - Jun 26 2009

Keywords

  • Acute myocardial infarction
  • Bare-metal stents
  • Drug-eluting stents
  • Late stent thrombosis
  • Restenosis

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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