Late-onset childhood occipital epilepsy (Gastaut type): A family study

Salvatore Grosso, Rossella Vivarelli, Giuseppe Gobbi, Rosanna D. Bartolo, Rosario Berardi, Paolo Balestri

Research output: Contribution to journalArticlepeer-review


Late onset childhood occipital epilepsy-Gastaut type (LOCOE) is a rare idiopathic epilepsy syndrome with an uncertain long-term prognosis. Elementary visual hallucinations and interictal spike-and-wave complexes in the occipital areas represent the main electroclinical findings of the syndrome. The functional nature of LOCOE has been emphasized together with the presence of genetic predisposition in the affected patients. Here, we report on two families in which two patients, respectively, showed electroclinical features compatible with LOCOE. Although further studies are needed to validate our observations, the involvement of two generations in one of the families we studied may corroborate the previously formulated hypothesis of an autosomal dominant model of inheritance in LOCOE. Of course, the identification of larger families is propaedeutic to linkage analysis studies.

Original languageEnglish
Pages (from-to)421-426
Number of pages6
JournalEuropean Journal of Paediatric Neurology
Issue number5
Publication statusPublished - Sep 2008


  • Epilepsy
  • Occipital lobe epilepsy
  • Partial seizures

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health
  • Neurology


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