Late relapse of embryonal rhabdomyosarcoma, botryoid variant, of the vagina

Roberto Vasquez, Paola Collini, Cristina Meazza, Francesca Favini, Michela Casanova, Andrea Ferrari

Research output: Contribution to journalArticle


We report on two very similar cases of vaginal embryonal RMS, botryoid variant, that relapsed 9 and 10 years after initial diagnosis, a few months after the menarche in both cases. A possible causal association with estrogen hormones is hypothesized, particularly for the second case described, in which estrogen receptors were negative in the primary tumor specimen and positive in the relapsing tumor specimen.

Original languageEnglish
Pages (from-to)140-141
Number of pages2
JournalPediatric Blood and Cancer
Issue number1
Publication statusPublished - Jul 2008


  • Chemotherapy
  • Hormone receptors
  • Menarche
  • Rhabdomyosarcoma

ASJC Scopus subject areas

  • Cancer Research
  • Pediatrics, Perinatology, and Child Health
  • Hematology

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