La prevalenza della sensibilizzazione da contatto al latice in pazienti consecutivi sottoposti a patch test

Translated title of the contribution: Latex contact sensitivity prevalence in consecutively patch tested patients

Paolo Lisi, Luca Stingeni, Rossano Hermes Valsecchi, Caterina Foti, Antonio Cristaudo, Paolo Daniele Pigatto, Nicola Balato, Simona Pelliccia

Research output: Contribution to journalArticle

Abstract

Background: natural rubber latex gloves and mainly their chemical additives are one of the most common causes of allergic contact dermatitis in many occupations. Objective: the aim of this study was to investigate the prevalence of delayed reactions to latex in consecutively patch tested patients. Materials and methods: 2 non-ammoniated latex extracts in 10% petrolatum, with different protein contents (0.48 and 1.28 mg/ml), and a series of latex additives were patch tested. The study was carried out in 2 phases: 695 patients with eczematous dermatitis and 312 subjects with chronic hand dermatitis who frequently used rubber gloves were investigated, respectively during the first and second period. Patients with a personal history of latex contact urticaria were excluded. Those with a positive path test reaction to latex were also prick tested. Results: no strongly positive or doubtful reactions were observed in 5 of the subjects investigated during the first phase (0.7%) and in 2 of those of second phase (0.6%). None of these showed positive reactions to latex additives patches or latex prick test. Conclusions: as delayed sensitivity to natural rubber latex is not frequent, its inclusion in the standard patch test series at present is not justified. Further studies will be needed to explain the reported differences in frequency of positive patch test reactions to latex, examining above all patients who use very often rubber gloves and suffer from chronic contact dermatitis of the hands.

Original languageItalian
Pages (from-to)22-26
Number of pages5
JournalAnnali Italiani di Dermatologia Allergologica Clinica e Sperimentale
Volume59
Issue number1
Publication statusPublished - Jan 2005

Fingerprint

Contact Dermatitis
Latex
Rubber
Patch Tests
Hand
Petrolatum
Allergic Contact Dermatitis
Eczema
Urticaria
Dermatitis
Occupations

ASJC Scopus subject areas

  • Dermatology

Cite this

La prevalenza della sensibilizzazione da contatto al latice in pazienti consecutivi sottoposti a patch test. / Lisi, Paolo; Stingeni, Luca; Valsecchi, Rossano Hermes; Foti, Caterina; Cristaudo, Antonio; Pigatto, Paolo Daniele; Balato, Nicola; Pelliccia, Simona.

In: Annali Italiani di Dermatologia Allergologica Clinica e Sperimentale, Vol. 59, No. 1, 01.2005, p. 22-26.

Research output: Contribution to journalArticle

Lisi, Paolo ; Stingeni, Luca ; Valsecchi, Rossano Hermes ; Foti, Caterina ; Cristaudo, Antonio ; Pigatto, Paolo Daniele ; Balato, Nicola ; Pelliccia, Simona. / La prevalenza della sensibilizzazione da contatto al latice in pazienti consecutivi sottoposti a patch test. In: Annali Italiani di Dermatologia Allergologica Clinica e Sperimentale. 2005 ; Vol. 59, No. 1. pp. 22-26.
@article{a36ee4ce95e6499bb1826b651c7c09ac,
title = "La prevalenza della sensibilizzazione da contatto al latice in pazienti consecutivi sottoposti a patch test",
abstract = "Background: natural rubber latex gloves and mainly their chemical additives are one of the most common causes of allergic contact dermatitis in many occupations. Objective: the aim of this study was to investigate the prevalence of delayed reactions to latex in consecutively patch tested patients. Materials and methods: 2 non-ammoniated latex extracts in 10{\%} petrolatum, with different protein contents (0.48 and 1.28 mg/ml), and a series of latex additives were patch tested. The study was carried out in 2 phases: 695 patients with eczematous dermatitis and 312 subjects with chronic hand dermatitis who frequently used rubber gloves were investigated, respectively during the first and second period. Patients with a personal history of latex contact urticaria were excluded. Those with a positive path test reaction to latex were also prick tested. Results: no strongly positive or doubtful reactions were observed in 5 of the subjects investigated during the first phase (0.7{\%}) and in 2 of those of second phase (0.6{\%}). None of these showed positive reactions to latex additives patches or latex prick test. Conclusions: as delayed sensitivity to natural rubber latex is not frequent, its inclusion in the standard patch test series at present is not justified. Further studies will be needed to explain the reported differences in frequency of positive patch test reactions to latex, examining above all patients who use very often rubber gloves and suffer from chronic contact dermatitis of the hands.",
keywords = "Delayed sensitivity, Latex, Path test, Prevalence",
author = "Paolo Lisi and Luca Stingeni and Valsecchi, {Rossano Hermes} and Caterina Foti and Antonio Cristaudo and Pigatto, {Paolo Daniele} and Nicola Balato and Simona Pelliccia",
year = "2005",
month = "1",
language = "Italian",
volume = "59",
pages = "22--26",
journal = "Annali Italiani di Dermatologia Allergologica Clinica e Sperimentale",
issn = "1592-6826",
publisher = "Il Pensiero Scientifico Editore s.r.l.",
number = "1",

}

TY - JOUR

T1 - La prevalenza della sensibilizzazione da contatto al latice in pazienti consecutivi sottoposti a patch test

AU - Lisi, Paolo

AU - Stingeni, Luca

AU - Valsecchi, Rossano Hermes

AU - Foti, Caterina

AU - Cristaudo, Antonio

AU - Pigatto, Paolo Daniele

AU - Balato, Nicola

AU - Pelliccia, Simona

PY - 2005/1

Y1 - 2005/1

N2 - Background: natural rubber latex gloves and mainly their chemical additives are one of the most common causes of allergic contact dermatitis in many occupations. Objective: the aim of this study was to investigate the prevalence of delayed reactions to latex in consecutively patch tested patients. Materials and methods: 2 non-ammoniated latex extracts in 10% petrolatum, with different protein contents (0.48 and 1.28 mg/ml), and a series of latex additives were patch tested. The study was carried out in 2 phases: 695 patients with eczematous dermatitis and 312 subjects with chronic hand dermatitis who frequently used rubber gloves were investigated, respectively during the first and second period. Patients with a personal history of latex contact urticaria were excluded. Those with a positive path test reaction to latex were also prick tested. Results: no strongly positive or doubtful reactions were observed in 5 of the subjects investigated during the first phase (0.7%) and in 2 of those of second phase (0.6%). None of these showed positive reactions to latex additives patches or latex prick test. Conclusions: as delayed sensitivity to natural rubber latex is not frequent, its inclusion in the standard patch test series at present is not justified. Further studies will be needed to explain the reported differences in frequency of positive patch test reactions to latex, examining above all patients who use very often rubber gloves and suffer from chronic contact dermatitis of the hands.

AB - Background: natural rubber latex gloves and mainly their chemical additives are one of the most common causes of allergic contact dermatitis in many occupations. Objective: the aim of this study was to investigate the prevalence of delayed reactions to latex in consecutively patch tested patients. Materials and methods: 2 non-ammoniated latex extracts in 10% petrolatum, with different protein contents (0.48 and 1.28 mg/ml), and a series of latex additives were patch tested. The study was carried out in 2 phases: 695 patients with eczematous dermatitis and 312 subjects with chronic hand dermatitis who frequently used rubber gloves were investigated, respectively during the first and second period. Patients with a personal history of latex contact urticaria were excluded. Those with a positive path test reaction to latex were also prick tested. Results: no strongly positive or doubtful reactions were observed in 5 of the subjects investigated during the first phase (0.7%) and in 2 of those of second phase (0.6%). None of these showed positive reactions to latex additives patches or latex prick test. Conclusions: as delayed sensitivity to natural rubber latex is not frequent, its inclusion in the standard patch test series at present is not justified. Further studies will be needed to explain the reported differences in frequency of positive patch test reactions to latex, examining above all patients who use very often rubber gloves and suffer from chronic contact dermatitis of the hands.

KW - Delayed sensitivity

KW - Latex

KW - Path test

KW - Prevalence

UR - http://www.scopus.com/inward/record.url?scp=23444460877&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=23444460877&partnerID=8YFLogxK

M3 - Articolo

VL - 59

SP - 22

EP - 26

JO - Annali Italiani di Dermatologia Allergologica Clinica e Sperimentale

JF - Annali Italiani di Dermatologia Allergologica Clinica e Sperimentale

SN - 1592-6826

IS - 1

ER -