Abstract
Background: natural rubber latex gloves and mainly their chemical additives are one of the most common causes of allergic contact dermatitis in many occupations. Objective: the aim of this study was to investigate the prevalence of delayed reactions to latex in consecutively patch tested patients. Materials and methods: 2 non-ammoniated latex extracts in 10% petrolatum, with different protein contents (0.48 and 1.28 mg/ml), and a series of latex additives were patch tested. The study was carried out in 2 phases: 695 patients with eczematous dermatitis and 312 subjects with chronic hand dermatitis who frequently used rubber gloves were investigated, respectively during the first and second period. Patients with a personal history of latex contact urticaria were excluded. Those with a positive path test reaction to latex were also prick tested. Results: no strongly positive or doubtful reactions were observed in 5 of the subjects investigated during the first phase (0.7%) and in 2 of those of second phase (0.6%). None of these showed positive reactions to latex additives patches or latex prick test. Conclusions: as delayed sensitivity to natural rubber latex is not frequent, its inclusion in the standard patch test series at present is not justified. Further studies will be needed to explain the reported differences in frequency of positive patch test reactions to latex, examining above all patients who use very often rubber gloves and suffer from chronic contact dermatitis of the hands.
| Original language | Italian |
|---|---|
| Pages (from-to) | 22-26 |
| Number of pages | 5 |
| Journal | Annali Italiani di Dermatologia Allergologica Clinica e Sperimentale |
| Volume | 59 |
| Issue number | 1 |
| Publication status | Published - Jan 2005 |
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ASJC Scopus subject areas
- Dermatology
Cite this
La prevalenza della sensibilizzazione da contatto al latice in pazienti consecutivi sottoposti a patch test. / Lisi, Paolo; Stingeni, Luca; Valsecchi, Rossano Hermes; Foti, Caterina; Cristaudo, Antonio; Pigatto, Paolo Daniele; Balato, Nicola; Pelliccia, Simona.
In: Annali Italiani di Dermatologia Allergologica Clinica e Sperimentale, Vol. 59, No. 1, 01.2005, p. 22-26.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - La prevalenza della sensibilizzazione da contatto al latice in pazienti consecutivi sottoposti a patch test
AU - Lisi, Paolo
AU - Stingeni, Luca
AU - Valsecchi, Rossano Hermes
AU - Foti, Caterina
AU - Cristaudo, Antonio
AU - Pigatto, Paolo Daniele
AU - Balato, Nicola
AU - Pelliccia, Simona
PY - 2005/1
Y1 - 2005/1
N2 - Background: natural rubber latex gloves and mainly their chemical additives are one of the most common causes of allergic contact dermatitis in many occupations. Objective: the aim of this study was to investigate the prevalence of delayed reactions to latex in consecutively patch tested patients. Materials and methods: 2 non-ammoniated latex extracts in 10% petrolatum, with different protein contents (0.48 and 1.28 mg/ml), and a series of latex additives were patch tested. The study was carried out in 2 phases: 695 patients with eczematous dermatitis and 312 subjects with chronic hand dermatitis who frequently used rubber gloves were investigated, respectively during the first and second period. Patients with a personal history of latex contact urticaria were excluded. Those with a positive path test reaction to latex were also prick tested. Results: no strongly positive or doubtful reactions were observed in 5 of the subjects investigated during the first phase (0.7%) and in 2 of those of second phase (0.6%). None of these showed positive reactions to latex additives patches or latex prick test. Conclusions: as delayed sensitivity to natural rubber latex is not frequent, its inclusion in the standard patch test series at present is not justified. Further studies will be needed to explain the reported differences in frequency of positive patch test reactions to latex, examining above all patients who use very often rubber gloves and suffer from chronic contact dermatitis of the hands.
AB - Background: natural rubber latex gloves and mainly their chemical additives are one of the most common causes of allergic contact dermatitis in many occupations. Objective: the aim of this study was to investigate the prevalence of delayed reactions to latex in consecutively patch tested patients. Materials and methods: 2 non-ammoniated latex extracts in 10% petrolatum, with different protein contents (0.48 and 1.28 mg/ml), and a series of latex additives were patch tested. The study was carried out in 2 phases: 695 patients with eczematous dermatitis and 312 subjects with chronic hand dermatitis who frequently used rubber gloves were investigated, respectively during the first and second period. Patients with a personal history of latex contact urticaria were excluded. Those with a positive path test reaction to latex were also prick tested. Results: no strongly positive or doubtful reactions were observed in 5 of the subjects investigated during the first phase (0.7%) and in 2 of those of second phase (0.6%). None of these showed positive reactions to latex additives patches or latex prick test. Conclusions: as delayed sensitivity to natural rubber latex is not frequent, its inclusion in the standard patch test series at present is not justified. Further studies will be needed to explain the reported differences in frequency of positive patch test reactions to latex, examining above all patients who use very often rubber gloves and suffer from chronic contact dermatitis of the hands.
KW - Delayed sensitivity
KW - Latex
KW - Path test
KW - Prevalence
UR - http://www.scopus.com/inward/record.url?scp=23444460877&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=23444460877&partnerID=8YFLogxK
M3 - Articolo
VL - 59
SP - 22
EP - 26
JO - Annali Italiani di Dermatologia Allergologica Clinica e Sperimentale
JF - Annali Italiani di Dermatologia Allergologica Clinica e Sperimentale
SN - 1592-6826
IS - 1
ER -