Laugier-Hunziker syndrome with familial distribution

Cataldo Patruno, Francesco Balato, Fabrizio Ayala, Nicola Balato

Research output: Contribution to journalArticle

Abstract

Laugier-Hunziker syndrome (LHS) is an acquired melanosis of lips and/or oral mucosa, in half the cases associated with melanonychia striata and, rarely, with hyperpigmentation of other mucocutaneous districts. LHS with familial distribution has rarely been reported in the literature; notwithstanding, at present it is considered a not uncommon condition. Histology is characterized by increased melanization of the lower layers of epidermis with no expansion of the melanocyte population. 3 relatives (mother and 2 daughters) with LHS of the oral cavity are reported. Differential diagnosis with other causes of oral pigmentation is discussed. Due to the familial distribution, Peutz-Jeghers syndrome must be differentiated for the absence of systemic disturbances and the normal number of melanocytes in the pigmented macules.

Original languageEnglish
Pages (from-to)61-63
Number of pages3
JournalAnnali Italiani di Dermatologia Clinica e Sperimentale
Volume53
Issue number2
Publication statusPublished - May 1999

Keywords

  • Hyperpigmentation
  • Labial melanotic macule
  • Laugier-Hunziker syndrome
  • Melanosis

ASJC Scopus subject areas

  • Dermatology

Fingerprint Dive into the research topics of 'Laugier-Hunziker syndrome with familial distribution'. Together they form a unique fingerprint.

  • Cite this