Lecture: management of chemotherapy-induced febrile neutropenia; guidelines and colony stimulating factors

Giuseppe Procopio, Monica Niger, Isabella Testa

Research output: Contribution to journalArticle

Abstract

Chemotherapy-induced febrile neutropenia (FN) is a major risk factor for severe infections potentially fatal, and also a dose-limiting toxicity, so causing dose reductions and/or delays in scheduled chemotherapy. This lecture provides recommendations for the use of G-CSF in adult cancer patients at risk of chemotherapy-induced FN. If expected risk of FN is equal or superior to 20%, a primary prophylaxis of FN with G-CSF is recommended. Primary prophylaxis can be considered in case of intermediate 10-20% risk of FN, in presence of factors that increase the frequency/risk of FN, such as age >65, advanced disease, prior episode of FN, poor performance status, radiotherapy to a wide body area (>20%). In case of low risk of FN (

Original languageEnglish
Pages (from-to)1-3
Number of pages3
JournalNeurological Sciences
DOIs
Publication statusAccepted/In press - 2011

Keywords

  • Chemotherapy-induced febrile neutropenia
  • Colony stimulating factors
  • Guidelines

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Clinical Neurology
  • Dermatology

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