Left and right atrial phasic function and deformation in untreated patients with prediabetes and type 2 diabetes mellitus

Marijana Tadic, Sanja Ilic, Cesare Cuspidi, Branislava Ivanovic, Ljiljana Bukarica, Nada Kostic, Tamara Marjanovic, Vesna Kocijancic, Vera Celic

Research output: Contribution to journalArticlepeer-review

Abstract

To evaluate phasic function and deformation of the left atrium (LA) and right atrium (RA) in subjects with prediabetes and type 2 diabetes mellitus. This cross-sectional study included 50 untreated normotensive subjects with prediabetes, 60 recently diagnosed normotensive diabetic patients and 60 healthy controls of similar sex and age. All the subjects underwent laboratory analyses and complete echocardiographic examination including strain analysis. LA and RA reservoir and conduit function gradually decreased, while booster pump increased, from the healthy controls, throughout the prediabetics, to the diabetics. The strain analysis of atrial phasic function showed more regular pattern of progressive atrial function deterioration than conventional evaluation with total, active and passive atrial function. In the whole study population HbA1c correlated with LA passive emptying fraction (r = −0.38, p 

Original languageEnglish
Pages (from-to)65-76
Number of pages12
JournalInternational Journal of Cardiovascular Imaging
Volume31
Issue number1
DOIs
Publication statusPublished - 2014

Keywords

  • Diabetes mellitus
  • Left atrium
  • Prediabetes
  • Right atrium
  • Strain analysis

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine
  • Medicine(all)

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