Left and right ventricle assessment with Cardiac CT: Validation study vs. Cardiac MR

Erica Maffei, Giancarlo Messalli, Chiara Martini, Koen Nieman, Onofrio Catalano, Alexia Rossi, Sara Seitun, Andrea I. Guaricci, Carlo Tedeschi, Nico R. Mollet, Filippo Cademartiri

Research output: Contribution to journalArticlepeer-review


Objectives To compare Magnetic Resonance (MR) and Computed Tomography (CT) for the assessment of left (LV) and right (RV) ventricular functional parameters. Methods Seventy nine patients underwent both Cardiac CT and Cardiac MR. Images were acquired using short axis (SAX) reconstructions for CT and 2D cine b-SSFP (balanced- steady state free precession) SAX sequence for MR, and evaluated using dedicated software. Results CT and MR images showed good agreement: LV EF (Ejection Fraction) (52±14% for CT vs. 52±14% for MR; r0 0.73; p>0.05); RV EF (47±12% for CT vs. 47±12% for MR; r00.74; p>0.05); LV EDV (End Diastolic Volume) (74± 21 ml/m 2 for CT vs. 76±25 ml/m 2 for MR; r00.59; p>0.05); RV EDV (84±25 ml/m 2 for CT vs. 80±23 ml/m 2 for MR; r0 0.58; p>0.05); LV ESV (End Systolic Volume)(37±19 ml/m 2 for CT vs. 38±23 ml/m 2 for MR; r00.76; p>0.05); RV ESV (46±21 ml/m 2 for CT vs. 43±18 ml/m 2 for MR; r00.70; p>0.05). Intra- and inter-observer variability were good, and the performance of CT was maintained for different EF subgroups. Conclusions Cardiac CT provides accurate and reproducible LVand RV volume parameters compared with MR, and can be considered as a reliable alternative for patients who are not suitable to undergo MR. Key Points • Cardiac-CT is able to provide Left and Right Ventricular function. • Cardiac-CT is accurate as MR for LV and RV volume assessment. • Cardiac-CT can provide accurate evaluation of coronary arteries and LV and RV function.

Original languageEnglish
Pages (from-to)1041-1049
Number of pages9
JournalEuropean Radiology
Issue number5
Publication statusPublished - May 2012


  • Cardiac computed tomography
  • Cardiac magnetic resonance
  • Ejection fraction
  • Left ventricle assessment
  • Right ventricle assessment

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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