Left ventricular aneurysm, aortic stenosis, and arcade mitral valve: Coexistence of three rare congenital heart defects

Francesca Romana Pluchinotta; Lisa A. Teot; Stephen P. Sanders

doi:10.1007/s00246-012-0251-6

Left ventricular aneurysm, aortic stenosis, and arcade mitral valve: Coexistence of three rare congenital heart defects

Francesca Romana Pluchinotta, Lisa A. Teot, Stephen P. Sanders

IRCCS Policlinico San Donato

Research output: Contribution to journal › Article › peer-review

Abstract

This report presents two fetuses with three rare congenital heart defects: congenital ventricular aneurysm, arcade mitral valve, and unicommissural aortic valve. Because interaction between the endocardium and the myocardium is essential for development of the myocardium and heart valves, the authors hypothesized that these three defects could be related to abnormal signaling between the endocardium and the myocardium during critical phases of cardiac development. This combination of defects might be incompatible with fetal survival to term.

Original language	English
Pages (from-to)	1206-1209
Number of pages	4
Journal	Pediatric Cardiology
Volume	33
Issue number	7
DOIs	https://doi.org/10.1007/s00246-012-0251-6
Publication status	Published - Oct 2012

Keywords

Aortic valve stenosis
Arcade-type mitral valve
Congenital heart disease
Ventricular aneurysm

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine
Pediatrics, Perinatology, and Child Health

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10.1007/s00246-012-0251-6

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abstract = "This report presents two fetuses with three rare congenital heart defects: congenital ventricular aneurysm, arcade mitral valve, and unicommissural aortic valve. Because interaction between the endocardium and the myocardium is essential for development of the myocardium and heart valves, the authors hypothesized that these three defects could be related to abnormal signaling between the endocardium and the myocardium during critical phases of cardiac development. This combination of defects might be incompatible with fetal survival to term.",

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AB - This report presents two fetuses with three rare congenital heart defects: congenital ventricular aneurysm, arcade mitral valve, and unicommissural aortic valve. Because interaction between the endocardium and the myocardium is essential for development of the myocardium and heart valves, the authors hypothesized that these three defects could be related to abnormal signaling between the endocardium and the myocardium during critical phases of cardiac development. This combination of defects might be incompatible with fetal survival to term.

KW - Aortic valve stenosis

KW - Arcade-type mitral valve

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KW - Ventricular aneurysm

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Left ventricular aneurysm, aortic stenosis, and arcade mitral valve: Coexistence of three rare congenital heart defects

Abstract

Keywords

ASJC Scopus subject areas

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