Left ventricular diastolic filling in elderly hypertensive patients

A. Nicolino, N. Ferrara, G. Longobardi, D. Acanfora, C. Rengo, F. Rengo

Research output: Contribution to journalArticlepeer-review


Objective: To evaluate the effects of mild to moderate hypertension and of LVH on diastolic filling and other Doppler indices in the elderly. Design: Survey with a control group. Subjects: Seventy-one hypertensives (34 men, 37 women) referred for echocardiograms and 32 age- and sex-matched normotensive volunteers. Thirty-six of the hypertensives had LVH; 34 did not. Setting: Echocardiographic laboratory. Measurements: M-mode, two-dimensional, and pulsed Doppler echocardiograms. A wide variety of Doppler-derived indices of diastolic function were assessed. Results: All Doppler derived indices of left ventricular diastolic filling (peak E, peak A, their ratio, EF slope, time-velocity integrals, atrial filling fraction, and isovolumic relaxation time) were similar among the three groups. Conclusion: Elderly mild to moderate hypertensives with or without LVH have LV diastolic filling that is normal for age. The identification of pathological diastolic dysfunction requires comparison to age-matched controls, since aging, a major factor influencing diastolic filling, can mask the effect of hypertension.

Original languageEnglish
Pages (from-to)217-222
Number of pages6
JournalJournal of the American Geriatrics Society
Issue number3
Publication statusPublished - 1993

ASJC Scopus subject areas

  • Geriatrics and Gerontology


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