Left ventricular dilatation and subclinical renal damage in primary hypertension

Elena Ratto, Francesca Viazzi, Barbara Bonino, Annalisa Gonnella, Debora Garneri, Emanuele L. Parodi, Gian Paolo Bezante, Lorenzo E. Derchi, Giovanna Leoncini, Roberto Pontremoli

Research output: Contribution to journalArticlepeer-review


OBJECTIVE:: A new classification of left ventricular geometry based on left ventricular dilatation and concentricity has recently been developed. This classification identifies subgroups differing with regard to systemic haemodynamics, left ventricular function and cardiovascular prognosis. We investigated the relationship between the new classification of left ventricular geometry and subclinical renal damage, namely urine albumin excretion and early intrarenal vascular changes in primary hypertensive patients. METHODS:: A total of 449 untreated hypertensive patients were studied. Four different patterns of left ventricular hypertrophy (eccentric nondilated, eccentric dilated, concentric nondilated and concentric dilated hypertrophy) were identified by echocardiography. Albuminuria was measured as the albumin-to-creatinine ratio. Early intrarenal vascular changes, expressed as the renal volume to resistive index ratio, were evaluated by ultrasound and Doppler scan. RESULTS:: Patients with concentric dilated left ventricular hypertrophy had higher albumin excretion rates (P=0.0258) and prevalence of microalbuminuria (P

Original languageEnglish
Pages (from-to)605-611
Number of pages7
JournalJournal of Hypertension
Issue number3
Publication statusPublished - Mar 6 2015


  • albuminuria
  • echocardiography
  • hypertension
  • left ventricular hypertrophy
  • nephrosclerosis

ASJC Scopus subject areas

  • Internal Medicine
  • Physiology
  • Cardiology and Cardiovascular Medicine


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