Left ventricular function in men and women. Another difference between sexes

C. Buonanno, E. Arbustini, L. Rossi, B. Dander, C. Vassanelli, B. Paris, A. Poppi

Research output: Contribution to journalArticlepeer-review


In a group of 70 patients, 29 women and 41 men, with atypical chest pain and normal findings at coronary arteriography, some hemodynamic and angiographic parameters of left ventricular function were measured, for the purpose of determining the values of normality and to document possible differences between sexes.Of the diastolic parameters, the left ventricular end-diastolic pressure and volume was lower in women than in men, the LVEDP being 11.9 ± 3.4 against 13.7 ± 3.6 mm Hg (P <0.025), and ED V of 76.1 ± 15 against 89.5 ± 23 ml/m2 (P <0.005).Of the systolic parameters, the ejection fraction of 74 ± 7% in women was significantly higher than that of 67 ± 7% in men (P <0.0005), and so was the mean velocity of volume reduction of 2.59 ± 0.58 of women against that of 2.26 ± 0.35 of men (P <0.01).The physiological diversity between the sexes, with women showing a constant hyperdynamic condition in comparison to men, with smaller ventricular volumes and increased contraction, seems to offer a possible explanation for some intriguing aspects of the diagnosis of ischemic heart disease in the female sex.

Original languageEnglish
Pages (from-to)525-528
Number of pages4
JournalEuropean Heart Journal
Issue number6
Publication statusPublished - Dec 1982


  • Coronary arteriography
  • Ventricular pressure
  • Ventricular volume

ASJC Scopus subject areas

  • Statistics, Probability and Uncertainty
  • Applied Mathematics
  • Physiology (medical)
  • Physiology
  • Cardiology and Cardiovascular Medicine


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