Left-ventricular hypertrophy and obesity: A systematic review and meta-analysis of echocardiographic studies

Cesare Cuspidi, Marta Rescaldani, Carla Sala, Guido Grassi

Research output: Contribution to journalArticle

Abstract

AIM: Left-ventricular hypertrophy (LVH) is a frequent complication in obese individuals; an updated review and meta-analysis focusing on this issue is lacking. Thus, we analysed the literature in order to provide a comprehensive information on the left-ventricular structural changes, as assessed by echocardiography, associated to obesity. DESIGN: A literature search using the keywords 'left ventricle', 'left-ventricular hypertrophy', 'cardiac hypertrophy', 'obesity', 'hypertension' and 'echocardiography' was performed in order to identify relevant papers. Full articles published in English language in the past 12 years reporting studies in adult obese individuals were considered. RESULTS: A total of 22 studies including 5486 obese individuals were considered. Overall, in the pooled obese population, prevalence of LVH, defined by 12 criteria, was 56.0% (range 20.0-85.0%). Data provided by 15 studies (n=4999 obese individuals), including 6623 non-obese controls, showed that the probability of having LVH was much higher in cases than in non-obese counterparts (odds ratio 4.19, 95% confidence interval 2.67-6.53, P

Original languageEnglish
Pages (from-to)16-25
Number of pages10
JournalJournal of Hypertension
Volume32
Issue number1
DOIs
Publication statusPublished - Jan 2014

Keywords

  • Echocardiography
  • Left-ventricular Hypertrophy
  • Obesity

ASJC Scopus subject areas

  • Internal Medicine
  • Physiology
  • Cardiology and Cardiovascular Medicine

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