Left ventricular remodelling in patients with moderate systolic dysfunction after myocardial infarction: Favourable effects of exercise training and predictive role of N-terminal pro-brain natriuretic peptide

Francesco Giallauria, Plinio Cirillo, Rosa Lucci, Mario Pacileo, Anna De Lorenzo, Mariantonietta D'Agostino, Sabino Moschella, Marianna Psaroudaki, Domenico Del Forno, Francesco Orio, Dino Franco Vitale, Massimo Chiariello, Carlo Vigorito

Research output: Contribution to journalArticle

Abstract

AIMS: To investigate the effects of exercise training (ET) on left ventricular (LV) volumes, cardiopulmonary functional capacity and N-terminal pro-brain natriuretic peptide (NT-proBNP) levels in postinfarction patients with moderate LV dysfunction. METHODS: Sixty-one postinfarction patients were randomized into two groups: group T [n=30, LV ejection fraction (EF) 41.6±11.3%, mean±SD] entered a 6-month ET programme, whereas group C (n=31, EF 42.0±7.6%, P=NS) did not. NT-proBNP assay, Doppler-echocardiography and cardiopulmonary exercise test were performed upon enrolment and at sixth months. RESULTS: At sixth months, trained patients showed an improvement in workload (+26%, P

Original languageEnglish
Pages (from-to)113-118
Number of pages6
JournalEuropean Journal of Cardiovascular Prevention and Rehabilitation
Volume15
Issue number1
DOIs
Publication statusPublished - Feb 2008

Keywords

  • Cardiac rehabilitation
  • Cardiopulmonary functional capacity
  • Exercise training
  • Left ventricular remodelling
  • Myocardial infarction
  • NT-proBNP

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Rehabilitation
  • Public Health, Environmental and Occupational Health

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  • Cite this

    Giallauria, F., Cirillo, P., Lucci, R., Pacileo, M., De Lorenzo, A., D'Agostino, M., Moschella, S., Psaroudaki, M., Del Forno, D., Orio, F., Vitale, D. F., Chiariello, M., & Vigorito, C. (2008). Left ventricular remodelling in patients with moderate systolic dysfunction after myocardial infarction: Favourable effects of exercise training and predictive role of N-terminal pro-brain natriuretic peptide. European Journal of Cardiovascular Prevention and Rehabilitation, 15(1), 113-118. https://doi.org/10.1097/HJR.0b013e3282f00990