Leigh disease: Value of CT in presymptomatic patients and variability of the lesions with time

Agostino Taccone, Maia Di Rocco, Paola Fondelli, Franco Cottafava

Research output: Contribution to journalArticle

Abstract

Three cases of Leigh disease (subacute necrotizing encephalomyelopathy) have been investigated recently in our institute by CT. Bilateral, low attenuation areas were observed in the basal ganglia in all cases. These areas corresponded to the typical necrosis areas seen pathologically in this disease. In our study there were further interesting CT appearances: The peripheral enhancement of low-density zones and the discovery of the lesions before the clear onset of clinical symptoms.

Original languageEnglish
Pages (from-to)207-210
Number of pages4
JournalJournal of Computer Assisted Tomography
Volume13
Issue number2
Publication statusPublished - 1989

Keywords

  • Brain, diseases
  • Computed tomography
  • Leigh disease
  • Spinal cord, diseases

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

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