Leiomyosarcoma of the pulmonary vein: Case report with immunohistochemical and ultrastructural findings

O. Leone, S. Piana, G. Cenacchi, P. A. Farneti, E. Pilato, D. Pacini, R. Galli, D. Santini, S. Pileri

Research output: Contribution to journalArticlepeer-review

Abstract

We report a case of neoplasia of pulmonary vein in a 45-year-old woman who presented with increasing dyspnea. As a consequence, the neoplasia filled the entire left atrium and appeared to be attached to the left superior pulmonary vein on surgical excision. Histologically, it was composed of a proliferation of sarcomatous cells, with a high mitotic rate and diffuse immunohistochemical positivity for smooth muscle actin, consistent with a leiomyosarcoma. The microscopic, immunohistochemical, and ultrastructural findings are discussed.

Original languageEnglish
Pages (from-to)235-240
Number of pages6
JournalGeneral and Diagnostic Pathology
Volume142
Issue number3-4
Publication statusPublished - 1997

Keywords

  • Dedifferentiation
  • Great vessels
  • Intimal sarcoma
  • Leiomyosarcoma
  • Pulmonary vein

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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