Leiomyosarcoma of the pulmonary vein: Case report with immunohistochemical and ultrastructural findings

O. Leone, S. Piana, G. Cenacchi, P. A. Farneti, E. Pilato, D. Pacini, R. Galli, D. Santini, S. Pileri

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

We report a case of neoplasia of pulmonary vein in a 45-year-old woman who presented with increasing dyspnea. As a consequence, the neoplasia filled the entire left atrium and appeared to be attached to the left superior pulmonary vein on surgical excision. Histologically, it was composed of a proliferation of sarcomatous cells, with a high mitotic rate and diffuse immunohistochemical positivity for smooth muscle actin, consistent with a leiomyosarcoma. The microscopic, immunohistochemical, and ultrastructural findings are discussed.

Original languageEnglish
Pages (from-to)235-240
Number of pages6
JournalGeneral and Diagnostic Pathology
Volume142
Issue number3-4
Publication statusPublished - 1997

Fingerprint

Leiomyosarcoma
Pulmonary Veins
Heart Atria
Dyspnea
Smooth Muscle
Actins
Neoplasms
Cell Proliferation

Keywords

  • Dedifferentiation
  • Great vessels
  • Intimal sarcoma
  • Leiomyosarcoma
  • Pulmonary vein

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Leiomyosarcoma of the pulmonary vein : Case report with immunohistochemical and ultrastructural findings. / Leone, O.; Piana, S.; Cenacchi, G.; Farneti, P. A.; Pilato, E.; Pacini, D.; Galli, R.; Santini, D.; Pileri, S.

In: General and Diagnostic Pathology, Vol. 142, No. 3-4, 1997, p. 235-240.

Research output: Contribution to journalArticle

Leone, O, Piana, S, Cenacchi, G, Farneti, PA, Pilato, E, Pacini, D, Galli, R, Santini, D & Pileri, S 1997, 'Leiomyosarcoma of the pulmonary vein: Case report with immunohistochemical and ultrastructural findings', General and Diagnostic Pathology, vol. 142, no. 3-4, pp. 235-240.
Leone, O. ; Piana, S. ; Cenacchi, G. ; Farneti, P. A. ; Pilato, E. ; Pacini, D. ; Galli, R. ; Santini, D. ; Pileri, S. / Leiomyosarcoma of the pulmonary vein : Case report with immunohistochemical and ultrastructural findings. In: General and Diagnostic Pathology. 1997 ; Vol. 142, No. 3-4. pp. 235-240.
@article{873608c1734a4e438e195eab421d92b5,
title = "Leiomyosarcoma of the pulmonary vein: Case report with immunohistochemical and ultrastructural findings",
abstract = "We report a case of neoplasia of pulmonary vein in a 45-year-old woman who presented with increasing dyspnea. As a consequence, the neoplasia filled the entire left atrium and appeared to be attached to the left superior pulmonary vein on surgical excision. Histologically, it was composed of a proliferation of sarcomatous cells, with a high mitotic rate and diffuse immunohistochemical positivity for smooth muscle actin, consistent with a leiomyosarcoma. The microscopic, immunohistochemical, and ultrastructural findings are discussed.",
keywords = "Dedifferentiation, Great vessels, Intimal sarcoma, Leiomyosarcoma, Pulmonary vein",
author = "O. Leone and S. Piana and G. Cenacchi and Farneti, {P. A.} and E. Pilato and D. Pacini and R. Galli and D. Santini and S. Pileri",
year = "1997",
language = "English",
volume = "142",
pages = "235--240",
journal = "General and Diagnostic Pathology",
issn = "0947-823X",
publisher = "Gustav Fischer Verlag",
number = "3-4",

}

TY - JOUR

T1 - Leiomyosarcoma of the pulmonary vein

T2 - Case report with immunohistochemical and ultrastructural findings

AU - Leone, O.

AU - Piana, S.

AU - Cenacchi, G.

AU - Farneti, P. A.

AU - Pilato, E.

AU - Pacini, D.

AU - Galli, R.

AU - Santini, D.

AU - Pileri, S.

PY - 1997

Y1 - 1997

N2 - We report a case of neoplasia of pulmonary vein in a 45-year-old woman who presented with increasing dyspnea. As a consequence, the neoplasia filled the entire left atrium and appeared to be attached to the left superior pulmonary vein on surgical excision. Histologically, it was composed of a proliferation of sarcomatous cells, with a high mitotic rate and diffuse immunohistochemical positivity for smooth muscle actin, consistent with a leiomyosarcoma. The microscopic, immunohistochemical, and ultrastructural findings are discussed.

AB - We report a case of neoplasia of pulmonary vein in a 45-year-old woman who presented with increasing dyspnea. As a consequence, the neoplasia filled the entire left atrium and appeared to be attached to the left superior pulmonary vein on surgical excision. Histologically, it was composed of a proliferation of sarcomatous cells, with a high mitotic rate and diffuse immunohistochemical positivity for smooth muscle actin, consistent with a leiomyosarcoma. The microscopic, immunohistochemical, and ultrastructural findings are discussed.

KW - Dedifferentiation

KW - Great vessels

KW - Intimal sarcoma

KW - Leiomyosarcoma

KW - Pulmonary vein

UR - http://www.scopus.com/inward/record.url?scp=0031042741&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031042741&partnerID=8YFLogxK

M3 - Article

C2 - 9065590

AN - SCOPUS:0031042741

VL - 142

SP - 235

EP - 240

JO - General and Diagnostic Pathology

JF - General and Diagnostic Pathology

SN - 0947-823X

IS - 3-4

ER -