TY - JOUR
T1 - Leishmaniasis of the eyelid mimicking an infundibular cyst and review of the literature on ocular leishmaniasis
AU - Veraldi, Stefano
AU - Bottini, Silvia
AU - Currò, Nicola
AU - Gianotti, Raffaele
PY - 2010/9
Y1 - 2010/9
N2 - Cutaneous leishmaniasis is an infection caused by protozoa belonging to the genus Leishmania. The disease is transmitted by sandflies. Reservoirs are represented by dogs, mice, rats, and wild rodents. Cutaneous leishmaniasis is usually characterized by a single, polymorphous lesion located in an uncovered area. We report a case of cutaneous leishmaniasis localized on the left upper eyelid in a 36-year-old woman. The disease was characterized by a single, asymptomatic nodule, which was clinically diagnosed as an inflammatory infundibular cyst. The lesion was excised surgically. Histopathological examination showed an inflammatory infiltrate consisting of lymphocytes, histiocytes, and plasma cells. Several Leishmania spp amastigotes were observed in the cytoplasm of macrophages. Culture examination on Novy-MacNeal-Nicolle medium was positive for Leishmania spp. PCR was positive for Leishmania infantum. No relapses were observed during follow-up (17 months). The purpose of this report is to emphasize the changeability of clinical presentation in cutaneous leishmaniasis.
AB - Cutaneous leishmaniasis is an infection caused by protozoa belonging to the genus Leishmania. The disease is transmitted by sandflies. Reservoirs are represented by dogs, mice, rats, and wild rodents. Cutaneous leishmaniasis is usually characterized by a single, polymorphous lesion located in an uncovered area. We report a case of cutaneous leishmaniasis localized on the left upper eyelid in a 36-year-old woman. The disease was characterized by a single, asymptomatic nodule, which was clinically diagnosed as an inflammatory infundibular cyst. The lesion was excised surgically. Histopathological examination showed an inflammatory infiltrate consisting of lymphocytes, histiocytes, and plasma cells. Several Leishmania spp amastigotes were observed in the cytoplasm of macrophages. Culture examination on Novy-MacNeal-Nicolle medium was positive for Leishmania spp. PCR was positive for Leishmania infantum. No relapses were observed during follow-up (17 months). The purpose of this report is to emphasize the changeability of clinical presentation in cutaneous leishmaniasis.
KW - Cutaneous leishmaniasis
KW - Leishmania spp
KW - Ocular leishmaniasis
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U2 - 10.1016/j.ijid.2009.07.024
DO - 10.1016/j.ijid.2009.07.024
M3 - Article
C2 - 19969498
AN - SCOPUS:77957350307
VL - 14
JO - International Journal of Infectious Diseases
JF - International Journal of Infectious Diseases
SN - 1201-9712
IS - SUPPL. 3
ER -