Abstract
Leptin is an adipokine that modulates multiple functions including energy homeostasis, thermoregulation, bone metabolism, endocrine and pro-inflammatory immune responses. Several studies have implicated leptin in the pathogenesis of chronic autoimmune inflammatory conditions such as autoimmune encephalomyelitis, intestinal bowel inflammation and type-1 diabetes. This review focuses on the role of leptin in non-autoimmune inflammatory diseases that include renal, liver and lung inflammation, atherosclerosis and metabolic syndrome, Behçet's disease and endometriosis.
Original language | English |
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Pages (from-to) | 285-291 |
Number of pages | 7 |
Journal | Inflammation and Allergy - Drug Targets |
Volume | 8 |
Issue number | 4 |
DOIs | |
Publication status | Published - 2009 |
Keywords
- Inflammation
- Leptin
- Metabolism
ASJC Scopus subject areas
- Immunology
- Immunology and Allergy
- Pharmacology