Abstract
Leptin is an adipokine that modulates multiple functions including energy homeostasis, thermoregulation, bone metabolism, endocrine and pro-inflammatory immune responses. Several studies have implicated leptin in the pathogenesis of chronic autoimmune inflammatory conditions such as autoimmune encephalomyelitis, intestinal bowel inflammation and type-1 diabetes. This review focuses on the role of leptin in non-autoimmune inflammatory diseases that include renal, liver and lung inflammation, atherosclerosis and metabolic syndrome, Behçet's disease and endometriosis.
| Original language | English |
|---|---|
| Pages (from-to) | 285-291 |
| Number of pages | 7 |
| Journal | Inflammation and Allergy - Drug Targets |
| Volume | 8 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 2009 |
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Keywords
- Inflammation
- Leptin
- Metabolism
ASJC Scopus subject areas
- Immunology
- Immunology and Allergy
- Pharmacology
Cite this
Leptin in non-autoimmune inflammation. / Cai, Chunlin; Hahn, Bevra H.; Matarese, Giuseppe; La Cava, Antonio.
In: Inflammation and Allergy - Drug Targets, Vol. 8, No. 4, 2009, p. 285-291.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Leptin in non-autoimmune inflammation
AU - Cai, Chunlin
AU - Hahn, Bevra H.
AU - Matarese, Giuseppe
AU - La Cava, Antonio
PY - 2009
Y1 - 2009
N2 - Leptin is an adipokine that modulates multiple functions including energy homeostasis, thermoregulation, bone metabolism, endocrine and pro-inflammatory immune responses. Several studies have implicated leptin in the pathogenesis of chronic autoimmune inflammatory conditions such as autoimmune encephalomyelitis, intestinal bowel inflammation and type-1 diabetes. This review focuses on the role of leptin in non-autoimmune inflammatory diseases that include renal, liver and lung inflammation, atherosclerosis and metabolic syndrome, Behçet's disease and endometriosis.
AB - Leptin is an adipokine that modulates multiple functions including energy homeostasis, thermoregulation, bone metabolism, endocrine and pro-inflammatory immune responses. Several studies have implicated leptin in the pathogenesis of chronic autoimmune inflammatory conditions such as autoimmune encephalomyelitis, intestinal bowel inflammation and type-1 diabetes. This review focuses on the role of leptin in non-autoimmune inflammatory diseases that include renal, liver and lung inflammation, atherosclerosis and metabolic syndrome, Behçet's disease and endometriosis.
KW - Inflammation
KW - Leptin
KW - Metabolism
UR - http://www.scopus.com/inward/record.url?scp=70349551430&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=70349551430&partnerID=8YFLogxK
U2 - 10.2174/187152809789352168
DO - 10.2174/187152809789352168
M3 - Article
C2 - 19754412
AN - SCOPUS:70349551430
VL - 8
SP - 285
EP - 291
JO - Current Drug Targets: Inflammation and Allergy
JF - Current Drug Targets: Inflammation and Allergy
SN - 1871-5281
IS - 4
ER -