Leptin in non-autoimmune inflammation

Chunlin Cai, Bevra H. Hahn, Giuseppe Matarese, Antonio La Cava

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Leptin is an adipokine that modulates multiple functions including energy homeostasis, thermoregulation, bone metabolism, endocrine and pro-inflammatory immune responses. Several studies have implicated leptin in the pathogenesis of chronic autoimmune inflammatory conditions such as autoimmune encephalomyelitis, intestinal bowel inflammation and type-1 diabetes. This review focuses on the role of leptin in non-autoimmune inflammatory diseases that include renal, liver and lung inflammation, atherosclerosis and metabolic syndrome, Behçet's disease and endometriosis.

Original languageEnglish
Pages (from-to)285-291
Number of pages7
JournalInflammation and Allergy - Drug Targets
Volume8
Issue number4
DOIs
Publication statusPublished - 2009

Fingerprint

Leptin
Inflammation
Encephalomyelitis
Adipokines
Body Temperature Regulation
Endometriosis
Type 1 Diabetes Mellitus
Atherosclerosis
Pneumonia
Homeostasis
Kidney
Bone and Bones
Liver

Keywords

  • Inflammation
  • Leptin
  • Metabolism

ASJC Scopus subject areas

  • Immunology
  • Immunology and Allergy
  • Pharmacology

Cite this

Leptin in non-autoimmune inflammation. / Cai, Chunlin; Hahn, Bevra H.; Matarese, Giuseppe; La Cava, Antonio.

In: Inflammation and Allergy - Drug Targets, Vol. 8, No. 4, 2009, p. 285-291.

Research output: Contribution to journalArticle

Cai, C, Hahn, BH, Matarese, G & La Cava, A 2009, 'Leptin in non-autoimmune inflammation', Inflammation and Allergy - Drug Targets, vol. 8, no. 4, pp. 285-291. https://doi.org/10.2174/187152809789352168
Cai, Chunlin ; Hahn, Bevra H. ; Matarese, Giuseppe ; La Cava, Antonio. / Leptin in non-autoimmune inflammation. In: Inflammation and Allergy - Drug Targets. 2009 ; Vol. 8, No. 4. pp. 285-291.
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