Abstract
The lesion detectability and quantification accuracy for a state-of-the-art integrated PET/CT system were investigated using Monte Carlo (MC) simulations. The 3D re-binned sinograms of true, scattered and total coincidence events were created from the simulated output list-mode data. The oncological 18F-FDG PET studies were simulated by using the MC code PET-EGS. It was observed that the recovery coefficients (RC) calculated on MC simulated realistic phantoms can be used to compensate for partial volume effect (PVE) in small neoplastic lesions in clinical studies. The results show that PET-EGS accuracy in reproducing the physical response of the considered PET/CT was >90%.
| Original language | English |
|---|---|
| Title of host publication | IEEE Nuclear Science Symposium Conference Record |
| Editors | S.D. Metzler |
| Pages | 3032-3035 |
| Number of pages | 4 |
| Volume | 5 |
| Publication status | Published - 2003 |
| Event | 2003 IEEE Nuclear Science Symposium Conference Record - Nuclear Science Symposium, Medical Imaging Conference - Portland, OR, United States Duration: Oct 19 2003 → Oct 25 2003 |
Other
| Other | 2003 IEEE Nuclear Science Symposium Conference Record - Nuclear Science Symposium, Medical Imaging Conference |
|---|---|
| Country | United States |
| City | Portland, OR |
| Period | 10/19/03 → 10/25/03 |
ASJC Scopus subject areas
- Computer Vision and Pattern Recognition
- Industrial and Manufacturing Engineering
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Cite this
Rizzo, C. G., Gilardi, M. C., Bettinardi, V., Savi, A., & Fazio, F. (2003). Lesion detectability and quantification in PET/CT oncological studies by Monte Carlo simulations. In S. D. Metzler (Ed.), IEEE Nuclear Science Symposium Conference Record (Vol. 5, pp. 3032-3035). [M14-180]