Letrozole and norethisterone acetate in rectovaginal endometriosis

Valentino Remorgida, Helena Luiza Abbamonte, Nicola Ragni, Ezio Fulcheri, Simone Ferrero

Research output: Contribution to journalArticlepeer-review


This open-label prospective study evaluated the efficacy of letrozole (2.5 mg/day) combined with norethisterone acetate (2.5 mg/day) in the treatment of pain symptoms related to the presence of rectovaginal endometriosis. The treatment significantly and quickly decreased the intensity of symptoms, but pain recurred at 3-month follow-up; five women underwent surgery during the follow-up, and histologic examination of rectovaginal nodules revealed the presence of active endometriotic lesions.

Original languageEnglish
Pages (from-to)724-726
Number of pages3
JournalFertility and Sterility
Issue number3
Publication statusPublished - Sep 2007

ASJC Scopus subject areas

  • Obstetrics and Gynaecology


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