Leukocyte counts in relation to the method of delivery during the first five days of life

Gaetano Chirico, Antonella Gasparoni, Laura Ciardelli, Lucia Martinotti, Giorgio Rondini

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

The goal of the present study was to evaluate total and differential leukocyte counts during the first 5 days of life in relation to the method of delivery. We included 203 healthy term infants; of these, 114 were born by vaginal delivery, and 89 by elective cesarean section. Total and differential leukocyte counts were evaluated at the following intervals: 0-6, 7-12, 13-24, 25-48, 49-72, 73-96, and 97-120 h after birth. The cord serum cortisol level was measured as an indicator of the degree of delivery-related stress. Mean leukocyte and neutrophil counts were higher in infants born by vaginal delivery in cord blood and up to 12 h of life. No significant differences were observed in the immature: total neutrophil ratios between the two groups of infants. The cord serum cortisol level was higher in vaginally delivered infants. A significant correlation was found between cortisol and leukocyte, neutrophil, or lymphocyte counts. The method of delivery produces significantly different total leukocyte and neutrophil counts during the first 12 h after birth; after this time, there appears to be no more variation of leukocyte counts during the first 5 days of life.

Original languageEnglish
Pages (from-to)294-299
Number of pages6
JournalBiology of the Neonate
Volume75
Issue number5
Publication statusPublished - May 1999

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Leukocyte Count
Neutrophils
Hydrocortisone
Parturition
Lymphocyte Count
Serum
Fetal Blood
Cesarean Section

Keywords

  • Cesarean section
  • Cortisol
  • Leukocytes
  • Neutrophils
  • Vaginal delivery

ASJC Scopus subject areas

  • Developmental Biology
  • Pediatrics, Perinatology, and Child Health

Cite this

Chirico, G., Gasparoni, A., Ciardelli, L., Martinotti, L., & Rondini, G. (1999). Leukocyte counts in relation to the method of delivery during the first five days of life. Biology of the Neonate, 75(5), 294-299.

Leukocyte counts in relation to the method of delivery during the first five days of life. / Chirico, Gaetano; Gasparoni, Antonella; Ciardelli, Laura; Martinotti, Lucia; Rondini, Giorgio.

In: Biology of the Neonate, Vol. 75, No. 5, 05.1999, p. 294-299.

Research output: Contribution to journalArticle

Chirico, G, Gasparoni, A, Ciardelli, L, Martinotti, L & Rondini, G 1999, 'Leukocyte counts in relation to the method of delivery during the first five days of life', Biology of the Neonate, vol. 75, no. 5, pp. 294-299.
Chirico, Gaetano ; Gasparoni, Antonella ; Ciardelli, Laura ; Martinotti, Lucia ; Rondini, Giorgio. / Leukocyte counts in relation to the method of delivery during the first five days of life. In: Biology of the Neonate. 1999 ; Vol. 75, No. 5. pp. 294-299.
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